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J-GLOBAL ID：200902163690417390   Reference number：02A0842841

Constitutive Activation of Proto-Oncogen Protein p21 Induces Cell Cycle Arrest in the G1 Phase in Contact-Inhibited Vascular Endothelial Cells.

プロトオンコジーン蛋白質p21の構成的活性化は接触阻害された血管内皮細胞においてG1相での細胞周期の停止を誘導する

Author (9)： SUZUKI E (Univ. Tokyo, Tokyo, JPN) ,  NISHIMATSU H (Univ. Tokyo, Tokyo, JPN) ,  NAGATA D (Univ. Tokyo, Tokyo, JPN) ,  SATONAKA H (Univ. Tokyo, Tokyo, JPN) ,  GOTO A (Univ. Tokyo, Tokyo, JPN) ,  OMATA M (Univ. Tokyo, Tokyo, JPN) ,  FUJITA T (Univ. Tokyo, Tokyo, JPN) ,  NAGAI R (Univ. Tokyo, Tokyo, JPN) ,  HIRATA Y (Univ. Tokyo, Tokyo, JPN)
Material： Hypertension Research  (Hypertens Res)
Volume： 25  Issue： 5  Page： 773-778  Publication year： Sep. 2002 
JST Material Number： Y0303A  ISSN： 0916-9636  Document type： Article
Article type： 原著論文  Country of issue： Germany, Federal Republic of (DEU)  Language： ENGLISH (EN)

Thesaurus term： human ,...
Semi thesaurus term： cdc2 kinase

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JST classification (3)： Biological function  (EB03040U) ,  Cell division and proliferation  (EF02020D) ,  Basic medicine on cardiovascular system  (GJ01020K)

Reference (29)：

• 1. Mokuno S, Ito T, Numaguchi Y, et al: Impaired nitric oxide production and enhanced autoregulation of coronary circulation in young spontaneously hypertensive rats at prehypertensive stage. Hypertens Res 2001; 24: 395-401.
• 2. Ross R: The pathogenesis of atherosclerosis: a perspective for the 1990s. Nature 1993; 362: 801-809.
• 3. Pines J: Cyclins and cyclin-dependent kinases: a biochemical view. Biochem J 1995; 308: 697-711.
• 4. Sherr CJ, Roberts JM: Inhibitors of mammalian G1 cyclin-dependent kinases. Genes Dev 1995; 9: 1149-1163.
• 5. El-Deiry WS, Tokino T, Velculescu VE, et al: WAF1, a potential mediator of p53 tumor suppression. Cell 1993; 75: 817-825.

Terms in the title (8)： プロトオンコジーン蛋白質 ,  p21 ,  構成的活性 ,  接触阻害 ,  血管内皮細胞 ,  G1相 ,  細胞周期 ,  誘導