Art

J-GLOBAL ID：200902163858199253   Reference number：02A0647418

Mechanism of Cytotoxicity of Paraquat.

パラコートの細胞毒性機構

Author (4)： FUKUSHIMA T (Fukuoka Univ., Fukuoka) ,  TANAKA K (Fukuoka Univ., Fukuoka) ,  LIM H (Fukuoka Univ., Fukuoka) ,  MORIYAMA M (Fukuoka Univ., Fukuoka)
Material： Environmental Health and Preventive Medicine  (Environ Health Prev Med)
Volume： 7  Issue： 3  Page： 89-94  Publication year： Jul. 2002 
JST Material Number： L2894A  ISSN： 1342-078X  CODEN： EHPMF7  Document type： Article
Article type： 文献レビュー  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *bipyridinium herbicide ,...

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JST classification (2)： Pesticides to weeds  (FB06030F) ,  Poisoning in general  (GD06010Q)

Substance index (1)： Paraquat

Reference (71)：

• ( 1 ) Bus JS, Aust SD and Gibson JE. Superoxide-and singlet oxygen-catalyzed lipid peroxidation as a possible mechanism for paraquat (methyl viologen) toxicity. Biochem. Biophys. Res. Commun. 1974; 58: 749-755.
• ( 2 ) Kato R, Iwasaki K and Noguchi H. Stimulatory effect of FMN and methyl viologen on cytochrome P-450 dependent reduction of tertiary amine N-oxide. Biochem. Biophys. Res. Commun. 1976; 72: 267-274.
• ( 3 ) Clejan L and Cederbaum AI. Synergistic interactions between NADPH-cytochrome P-450 reductase, paraquat, and iron in the generation of active oxygen radicals. Biochem. Pharmacol. 1989; 38: 1779-1786.
• ( 4 ) Talcott RE, Shu H and Wei ET. Dissociation of microsomal oxygen reduction and lipid peroxidation with the electron acceptors, paraquat and menadione. Biochem. Pharmacol. 1979; 28: 665-671.
• ( 5 ) Castro GD, Lopez A and Castro JA. Evidence for hydroxyl free radical formation during paraquat but not for nifurtimox liver microsomal biotransformation. A dimethyl-sulfoxide scavenging study. Arch. Toxicol. 1988; 62: 355-358.

Terms in the title (2)： パラコート ,  細胞毒性