Art

J-GLOBAL ID：200902164516544664   Reference number：99A1041819

Neuron-specific Cdk5 Kinase Is Responsible for Mitosis-Independent Phosphorylation of c-Src at Ser75 in Human Y79 Retinoblastoma Cells.

ヒトY79網膜芽細胞腫細胞において,神経細胞特異的Cdk5キナーゼがc-SrcのSer75における細胞分裂非依存りん酸化に関与する

Author (2)： KATO G (Yamanashi Medical Univ., Yamanashi) ,  MAEDA S (Yamanashi Medical Univ., Yamanashi)
Material： Journal of Biochemistry  (J Biochem)
Volume： 126  Issue： 5  Page： 957-961  Publication year： Nov. 01, 1999 
JST Material Number： F0286A  ISSN： 0021-924X  CODEN： JOBIAO  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： human ,...
Semi thesaurus term： retinoblastoma ,...

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JST classification (2)： Cell division and proliferation  (EF02020D) ,  Enzyme in general  (EB09010D)

Substance index (2)： Serine ,  γ-Butyrolactone

Reference (32)：

• BROWN, M. T. Regulation, substrates and functions of src. Biochim. Biophys. Acta. 1996, 1287, 121-149
• THOMAS, S. M. Cellular functions regulated by Src family kinases. Annu. Rev. Cell. Dev. Biol. 1997, 13, 513-609
• CHACKALAPARAMPIL, I. Altered phosphorylation and activation of pp60^<c-src> during fibroblast mitosis. Cell. 1988, 52, 801-810
• SHENOY, S. Purified maturation promoting factor phosphorylates pp60^<c-src> at the sites phosphorylated during fibroblast mitosis. Cell. 1989, 57, 763-774
• MORGAN, D. O. Mitosis-specific phosphorylation of p60^<c-src> by p34^<cdc2>-associated protein kinase. Cell. 1989, 57, 775-786

Terms in the title (9)： ヒト ,  網膜芽細胞腫 ,  細胞 ,  神経細胞 ,  Cdk5キナーゼ ,  c-Src ,  細胞分裂 ,  非依存 ,  りん酸化