Art

J-GLOBAL ID：200902165084563987   Reference number：02A0339249

Protective effect of the hooks and stems of Uncaria sinensis against nitric oxide donor-induced neuronal death in cultured cerebellar granule cells.

培養小脳か粒細胞におけるNoドナー誘導神経細胞死に対するUncaria sinensisの鈎きょくおよび茎の保護作用

Author (8)： SHIMADA Y (Toyama Medical and Pharmaceutical Univ., Toyama, JPN) ,  YOKOYAMA K (Toyama Medical and Pharmaceutical Univ., Toyama, JPN) ,  GOTO H (Toyama Medical and Pharmaceutical Univ., Toyama, JPN) ,  SAKAKIBARA I (Tsumura Central Res. Lab., Ibaraki, JPN) ,  SEKIYA N (Toyama Medical and Pharmaceutical Univ., Toyama, JPN) ,  MANTANI N (Toyama Medical and Pharmaceutical Univ., Toyama, JPN) ,  SAKAI S (Toyama Medical and Pharmaceutical Univ., Toyama, JPN) ,  TERASAWA K (Toyama Medical and Pharmaceutical Univ., Toyama, JPN)
Material： Journal of Traditional Medicines  (和漢医薬学雑誌)
Volume： 19  Issue： 1  Page： 15-20  Publication year： Feb. 20, 2002 
JST Material Number： Y0941A  ISSN： 1880-1447  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： Rubiaceae ,...
Semi thesaurus term： NOドナー ,...

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JST classification (1)： Basic research of pharmacology of crude drugs  (GX06020J)

Substance index (1)： SIN-1

Reference (28)：

• BOLANOS, J. P. Roles of nitric oxide in brain hypoxia-ischemia. Biochim. Biophys. Acta. 1999, 1411, 415-436
• LIPTON, S. A. Excitatory amino acid as a final common pathway for neurologic disorders. N. Engl. J. Med. 1994, 330, 613-622
• ROTHMAN, S. M. Glutamate and the pathophysiology of hypoxic-ischemic brain damage. Ann. Neurol. 1986, 19, 105-111
• DAWSON, V. L. Nitric oxide mediates glutamate neurotoxicity in primary cortical cultures. Proc. Natl. Acad. Sci. USA. 1991, 88, 6368-6371
• NOMURA, Y. Inducible nitric oxide synthase in glial cells. Neurosci. Res. 1993, 18, 103-107

Terms in the title (9)： 培養 ,  小脳か粒細胞 ,  NOドナー ,  誘導 ,  神経細胞死 ,  Uncaria ,  鈎 ,  茎 ,  保護作用