Art
J-GLOBAL ID：200902165439576988   Reference number：00A0463871

Phosphorylated Morpholine Acetal Human Neurokinin-1 Receptor Antagonists as Water-Soluble Prodrugs.

水溶性プロドラッグとしてのりん酸化モルホリンアセタール系ヒトニューロキニン-1受容体きっ抗薬
Author (9)：
HALE J J

About HALE J J

(Merck Res. Lab., New Jersey)

About Merck Res. Lab., New Jersey

, 
MILLS S G

About MILLS S G

(Merck Res. Lab., New Jersey)

About Merck Res. Lab., New Jersey

, 
DORN C P

About DORN C P

(Merck Res. Lab., New Jersey)

About Merck Res. Lab., New Jersey

, 
BUDHU R J

About BUDHU R J

(Merck Res. Lab., New Jersey)

About Merck Res. Lab., New Jersey

, 
CHICCHI G G

About CHICCHI G G

(Merck Res. Lab., New Jersey)

About Merck Res. Lab., New Jersey

, 
KURTZ M M

About KURTZ M M

(Merck Res. Lab., New Jersey)

About Merck Res. Lab., New Jersey

, 
BER E

About BER E

(Merck Res. Lab., New Jersey)

About Merck Res. Lab., New Jersey

, 
METZGER J M

About METZGER J M

(Merck Res. Lab., New Jersey)

About Merck Res. Lab., New Jersey

, 
MACINTYRE D E

About MACINTYRE D E

(Merck Res. Lab., New Jersey)

About Merck Res. Lab., New Jersey


Material：
Journal of Medicinal Chemistry  (J Med Chem)

About Journal of Medicinal Chemistry


Volume： 43  Issue： 6  Page： 1234-1241  Publication year： Mar. 23, 2000 
JST Material Number： D0102A  ISSN： 0022-2623  CODEN： JMCMAR  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)
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*nitrogen heterocyclic compound

About nitrogen heterocyclic compound

,...
Semi thesaurus term：
Thesaurus term/Semi thesaurus term
Keywords indexed to the article.
All keywords is available on JDreamIII(charged).
On J-GLOBAL, this item will be available after more than half a year after the record posted. In addtion, medical articles require to login to MyJ-GLOBAL.
cisplatin

About cisplatin

,...
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JST classification (2)：
JST classification
Category name(code) classified by JST.
Basic research of anti-inflammatory drugs 
(GW15010T)

About Basic research of anti-inflammatory drugs

,  Oxazines 
(CF07100X)

About Oxazines

Substance index (4)：
Substance index
Chemical Substance indexed to the Article.
L-742694

About L-742694

, 
Aprepitant

About Aprepitant

, 
[3-[[(2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholino]methyl]-5-oxo-4,5-dihydro-1H-1,2,4-triazole-1-yl]phosphonic acid

About [3-[[(2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholino]methyl]-5-oxo-4,5-dihydro-1H-1,2,4-triazole-1-yl]phosphonic acid

, 
N-Methyl-D-glucamine

About N-Methyl-D-glucamine

Terms in the title (8)：
Terms in the title
Keywords automatically extracted from the title.
水溶性

About 水溶性

, 
プロドラッグ

About プロドラッグ

, 
りん酸化

About りん酸化

, 
モルホリン

About モルホリン

, 
アセタール

About アセタール

, 
ヒト

About ヒト

, 
ニューロキニン

About ニューロキニン

, 
受容体きっ抗薬

About 受容体きっ抗薬


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