Art

J-GLOBAL ID：200902166253646508   Reference number：03A0087570

Total Synthesis of (±)-Wortmannin.

(±)-ウォルトマンニンの全合成

Author (4)： MIZUTANI T (Univ. Tokyo, Tokyo, JPN) ,  HONZAWA S (Univ. Tokyo, Tokyo, JPN) ,  TOSAKI S (Univ. Tokyo, Tokyo, JPN) ,  SHIBASAKI M (Univ. Tokyo, Tokyo, JPN)
Material： Angewandte Chemie. International Edition  (Angewandte Chemie. International Edition in English)
Volume： 41  Issue： 24  Page： 4680-4682  Publication year： Dec. 16, 2002 
JST Material Number： H0127B  ISSN： 1433-7851  CODEN： ACIEAY  Document type： Article
Article type： 短報  Country of issue： Germany, Federal Republic of (DEU)  Language： ENGLISH (EN)

Thesaurus term： heterosteroid ,...
Semi thesaurus term： Penicillium Wortmannii

   To see more with JDream III (charged).   {{ this.onShowAbsJLink("http://jdream3.com/lp/jglobal/index.html?docNo=03A0087570&from=J-GLOBAL&jstjournalNo=H0127B") }}

JST classification (2)： Condensed derivatives of pyrane  (CF07093I) ,  Enzyme in general  (EB09010D)

Substance index (20)： Wortmannin ,  1α-(Methoxymethyl)-11α-(tert-butyldimethylsiloxy)-6,7-[methoxymethylenebis(oxy)]-17,17-[ethylenebis(oxy)]-2-oxa-5α-androsta-8-ene-3-one ,  (1E)-2-(Benzyloxy)-11β-[[2-(trimethylsilyl)ethoxy]methoxy]-17,17-[ethylenebis(oxy)]-5-desethyl-2,3-secoandrosta-1,8-diene ,  (3aS,6S,7aS)-4-[(4Z)-4-Methyl-6-(benzyloxy)-4-hexenyl]-5-(trifluoromethylsulfonyloxy)-6-[[2-(trimethylsilyl)ethoxy]methoxy]-7a-methyl-3a,6,7,7a-tetrahydrospiro[indan-1,2′-[1,3]dioxolane] ,  (3aα,4S)-1,5-Dioxo-7aβ-methylhydrindane-4α-carboxylic acid methyl ester ,  (3aS)-4-Allyl-5-[(trifluoromethyl)sulfonyloxy]-6β-hydroxy-7aβ-methyl-2,3,3aα,6,7,7a-hexahydrospiro[1H-indene-1,2′-[1,3]dioxolane] ,  (3aS)-4-Allyl-5-[(trifluoromethyl)sulfonyloxy]-6β-[[2-(trimethylsilyl)ethoxy]methoxy]-7aβ-methyl-2,3,3aα,6,7,7a-hexahydrospiro[1H-indene-1,2′-[1,3]dioxolane] ,  (Z)-1-(Benzyloxy)-3-iodo-2-butene ,  (1E)-2-(Benzyloxy)-11α-hydroxy-17,17-[ethylenebis(oxy)]-5-desethyl-2,3-secoandrosta-1,8-diene ,  (1S)-1,2-Dihydroxy-11α-(tert-butyldimethylsiloxy)-17,17-[ethylenebis(oxy)]-5-desethyl-2,3-secoandrosta-8-ene ,  (1S)-1-Acetoxy-2-methoxy-11α-(tert-butyldimethylsiloxy)-17,17-[ethylenebis(oxy)]-5-desethyl-2,3-secoandrosta-8-ene ,  (1S)-1-Acetoxy-2-methoxy-11α-(tert-butyldimethylsiloxy)-17,17-[ethylenebis(oxy)]-5-desethyl-2,3-secoandrosta-8-ene-7-one ,  (1S)-1-Acetoxy-2-methoxy-6-(allyloxy)-11α-(tert-butyldimethylsiloxy)-17,17-[ethylenebis(oxy)]-5-desethyl-2,3-secoandrosta-5,8-diene-7-one ,  (1S)-1-Acetoxy-1-(methoxymethyl)-6,7-[methoxymethylenebis(oxy)]-11α-(tert-butyldimethylsiloxy)-17,17-[ethylenebis(oxy)]-1,2-seco-5α-androsta-2,8-diene ,  (1S)-1-Acetoxy-2-methoxy-6,7-[methoxymethylenebis(oxy)]-11α-(tert-butyldimethylsiloxy)-17,17-[ethylenebis(oxy)]-3-oxo-2,3-seco-5α-androsta-8-ene ,  1α-(Methoxymethyl)-4-[(Z)-hydroxymethylene]-11α-(tert-butyldimethylsiloxy)-6,7-[methoxymethylenebis(oxy)]-17,17-[ethylenebis(oxy)]-2-oxa-5α-androsta-8-ene-3-one ,  1α-(Methoxymethyl)-4-(methoxymethylene)-11α-(tert-butyldimethylsiloxy)-6,7-dihydroxy-17,17-[ethylenebis(oxy)]-2-oxa-5α-androsta-8-ene-3-one ,  1α-(Methoxymethyl)-4-(methoxymethylene)-11α-(tert-butyldimethylsiloxy)-6α-hydroxy-17,17-[ethylenebis(oxy)]-2-oxa-5α-androsta-8-ene-3,7-dione ,  1α-(Methoxymethyl)-4-(methoxymethylene)-11α-(tert-butyldimethylsiloxy)-6-hydroxy-17,17-[ethylenebis(oxy)]-2-oxaandrosta-5,8-diene-3,7-dione ,  (1S)-1,6bβ,7,8,9a,10,11,11b-Octahydro-11β-(tert-butyldimethylsiloxy)-1-(methoxymethyl)-9aα,11bα-dimethyl-3H-furo[4,3,2-de]indeno[4,5-h]-2-benzopyran-3,6,9-trione

Terms in the title (2)： ウォルトマンニン ,  全合成