Art

J-GLOBAL ID：200902169226000786   Reference number：02A0544271

Hypoxia Enhances the Expression of Plasminogen Activator Inhibitor-1 in Human Lung Cancer Cells, EBC-1.

低酸素はヒト肺癌細胞EBC-1におけるプラスミノーゲン活性化因子阻害剤1の発現を促進する

Author (9)： KIMURA D (Hirosaki Univ. School of Meidicine, Hirosaki) ,  IMAIZUMI T (Hirosaki Univ. School of Meidicine, Hirosaki) ,  TAMO W (Hirosaki Univ. School of Meidicine, Hirosaki) ,  SAKAI T (Hirosaki Univ. School of Meidicine, Hirosaki) ,  ITO K (Hirosaki Univ. School of Meidicine, Hirosaki) ,  HATANAKA R (Hirosaki Univ. School of Meidicine, Hirosaki) ,  YOSHIDA H (Hirosaki Univ. School of Meidicine, Hirosaki) ,  SATOH K (Hirosaki Univ. School of Meidicine, Hirosaki) ,  FUKUDA I (Hirosaki Univ. School of Meidicine, Hirosaki)
Material： Tohoku Journal of Experimental Medicine  (Tohoku J Exp Med)
Volume： 196  Issue： 4  Page： 259-267  Publication year： Apr. 2002 
JST Material Number： G0649A  ISSN： 0040-8727  CODEN： TJEMAO  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： cultured cell ,...
Semi thesaurus term： *PAI1 ,...

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JST classification (1)： Chemistry,biochemistry and pathology of tumors(=neoplasms)  (GE02030N)

Substance index (2)： Actinomycin D ,  MG-132

Reference (32)：

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• Descheemaeker, K.A., Wyns, S., Nelles, L., Auwerx, J., Ny, T. & Collen, D. (1992) Interaction of AP-1-, AP-2-, and Sp1-like proteins with two distinct sites in the upstream regulatory region of the plasminogen activator inhibitor-1 gene mediates the phorbol 12-myristate 13-acetate response. J. Biol. Chem., 267, 15086-15091.
• Duffy, M.J. (1992) The role of proteolytic enzymes in cancer invasion and metastasis. Clin. Exp. Metastasis, 10, 145-155.
• Feener, E.P., Northrup, J.M., Aiello, L.P. & King, G.L. (1995) Angiotensin II induces plasminogen activator inhibitor-1 and -2 expression in vascular endothelial and smooth muscle cells. J. Clin. Invest., 95, 1353-1362.

Terms in the title (7)： 低酸素 ,  ヒト ,  肺癌細胞 ,  EBC ,  プラスミノーゲン活性化因子阻害剤1 ,  発現 ,  促進