Art

J-GLOBAL ID：200902169644890950   Reference number：99A0954147

Origin and treatment of insulin resistance.

インスリン抵抗性の成因と治療

Author (3)： KASUGA MASATO (神戸大) ,  FUNABIKI AYUMI (神戸大) ,  MORITA SUMIHARU (神戸大)
Material： 日本内科学会雑誌  (Journal of the Japanese Society of Internal Medicine)
Volume： 88  Issue： 9  Page： 1860-1864  Publication year： Sep. 10, 1999 
JST Material Number： F0916A  ISSN： 0021-5384  CODEN： NNGAA  Document type： Article
Article type： 解説  Country of issue： Japan (JPN)  Language： JAPANESE (JA)

Thesaurus term： pathogenesis ,...
Semi thesaurus term： *insulin resistance

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JST classification (1)： Treatment for metabolic diseases,nutritional diseases.  (GD05030F)

Substance index (4)： Fenformin ,  Metformin ,  Troglitazone ,  Pioglitazone

Reference (14)：

• 1) Matthews DR, et al: Homeostasis model assessment: insulin resistance and β-cell function from fasting plasma glucose and insulin concentration in man. Diabetologia 28: 412-419, 1985.
• 2) 荒木悟,春日雅人:インスリン受容体遺伝子.日本臨床増刊号糖尿病 403-408, 1997.
• 3) Martin BC, et al: Role of glucose and insulin resistance in development of type 2 deabetes mellitus: results of a 25-year follow-up study. Lancet 340: 925-929, 1992.
• 4) Eriksson J, et al: Early metabolic defects in persons at increased risk for non-insulin-dependent diabetes mellitus. N Engl J Med 321: 337-343, 1989.
• 5) Rothman DL, et al: Decreased muscle glucose transport/phosphorylation is an early defect in the pathogenesis of non-insulin-dependent. Proc Natl Acad Sci USA 92: 983-987, 1995.

Terms in the title (3)： インスリン抵抗性 ,  成因 ,  治療