Art

J-GLOBAL ID：200902169761866610   Reference number：99A0599141

Bone Marrow Toxicity of Doxorubicin(DXR) Encapsulated in Polyethylene Glycol-Coated Liposomes.

ドキソルビシン封入ポリエチレングリコール修飾リポソームの骨髄毒性

Author (7)： HOSODA JUN'ICHI (東京医大 病院) ,  UNEZAKI SAKAE (東京医大 病院) ,  MATSUMURA MASAFUMI (東京医大 病院) ,  MAE AKIRA (東京医大 病院) ,  MARUYAMA KAZUO (帝京大 薬) ,  IWATSURU MOTOHARU (帝京大 薬) ,  TSUCHIYA SEISHI (東京薬大 薬)
Material： 薬剤学  (Journal of Pharmaceutical Science and Technology, Japan)
Volume： 59  Issue： 2  Page： 51-56  Publication year： Jun. 1999 
JST Material Number： G0234A  ISSN： 0372-7629  CODEN： YAKUA  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： JAPANESE (JA)

Thesaurus term： animal test ,...
Semi thesaurus term： hare

   To see more with JDream III (charged).   {{ this.onShowAbsJLink("http://jdream3.com/lp/jglobal/index.html?docNo=99A0599141&from=J-GLOBAL&jstjournalNo=G0234A") }}

JST classification (2)： Basic research of antitumor(=antineoplastic)antibiotics  (GX05040Y) ,  Basic biopharmacy  (GY01021U)

Substance index (1)： Doxorubicin

Reference (11)：

• UNEZAKI, S. Enhanced tumor targeting and improved antitumor activity of doxorubicin by long-circulating liposomes containing amphipathic poly(ethylene glycol). Int. J. Pharm. 1995, 126, 41-48
• HOSODA, J. Antitumor activity of doxorubicin encapsulated in poly(ethylene glycol)-coated liposomes. Biol. Pharm. Bull. 1995, 18, 1234-1237
• UNEZEKI, S. Direct measurement of the extravasation of polyethylene glycol-coated liposomes into solid tumor tissue by in vivo fluorescence microscopy. Int. J. Pharm. 1996, 144, 11-17
• MARUYAMA, K. Prolonged circulation time in vivo of large unilamellar liposomes composed of distearoylphosphatidylcholine and cholesterol containing amphipathic poly(ethylene glycol). Biochim. Biophys. Acta. 1992, 1128, 44-49
• SZOKA, F. Procedure for preparation of liposomes with large internal aqueous space and high capture by reverse-phase evaporation. Proc. Natl. Acad. Sci. USA. 1978, 75, 4194-4198

Terms in the title (4)： ドキソルビシン ,  封入 ,  ポリエチレングリコール修飾リポソーム ,  骨髄毒性