Art

J-GLOBAL ID：200902170081112856   Reference number：99A0461760

Effect of Thiazinotrienomycin B, an Ansamycin Antibiotic, on the Function of Epidermal Growth Factor Receptor in Human Stomach TumorCells.

ヒトの胃腫よう細胞におけるEGF受容体機能に対する,アンサマイシン系抗生物質のチアジノトリエノマイシンBの作用

Author (5)： HOSOKAWA N (Inst. Microbial Chemistry, Tokyo, JPN) ,  YAMAMOTO S (Showa Coll. Pharmaceutical Sci., Tokyo, JPN) ,  UEHARA Y (National Inst. Infectious Diseases, Tokyo, JPN) ,  HORI M (Showa Coll. Pharmaceutical Sci., Tokyo, JPN) ,  S.-TSUCHIYA K (Showa Coll. Pharmaceutical Sci., Tokyo, JPN)
Material： Journal of Antibiotics  (J Antibiot)
Volume： 52  Issue： 5  Page： 485-490  Publication year： May. 25, 1999 
JST Material Number： G0489A  ISSN： 0021-8820  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *antibiotics ,...
Semi thesaurus term： Streptomyces ,...

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JST classification (1)： Basic research of antitumor(=antineoplastic)antibiotics  (GX05040Y)

Substance index (1)： Thiazinotrienomycin B

Reference (10)：

• 1) TAHARA, E.: Growth factors and oncogenes in human gastrointestinal carcinomas. J. Cancer Res. Clin. Oncol. 116: 121-131, 1990
• 2) GURPIDE, E.: Endometrial cancer: biochemical and clinical correlates. J. Natl.Cancer Inst. 83: 405-416, 1991
• 3) WONG, D. T.: TGF-alpha and oral carcinogenesis. Eur. J. Cancer B Oral Oncol. 29B: 3-7, 1993
• 4) YOSHIDA, K.; T. TSUDA, T. MATSUMURA, T. TSUJINO, T. HATTORI, H. ITO & E. TAHARA: Amplification of epidermal growth factor receptor (EGFR) gene and oncogenes in human gastric carcinomas. Virchows Arch. B Cell Pathol. Incl. Mol. Pathol. 57: 285-290, 1989
• 5) YOSHIDA, K.; E. KYO, T. TSUJINO, T. SANO, M. NIIMOTO & E. TAHARA: Expression of epidermal growth factor, transforming growth factor-altha and their receptor genes in human gastric carcinomas; implication for autocrine growth. Jpn. J. Cancer Res. 81:43-51,1990

Terms in the title (7)： ヒト ,  胃 ,  腫よう細胞 ,  EGF受容体 ,  アンサマイシン ,  抗生物質 ,  チアジノトリエノマイシンB