Art

J-GLOBAL ID：200902171145391238   Reference number：02A0156045

Membrane Topology of a Multidrug Efflux Transporter, AcrB, in Escherichia coli.

大腸菌の多剤排出輸送体AcrBの膜トポロジー

Author (3)： Fujihira E (Osaka Univ., Osaka) ,  Tamura N (Osaka Univ., Osaka) ,  Yamaguchi A (Osaka Univ., Osaka)
Material： Journal of Biochemistry  (J Biochem)
Volume： 131  Issue： 1  Page： 145-151  Publication year： Jan. 01, 2002 
JST Material Number： F0286A  ISSN： 0021-924X  CODEN： JOBIAO  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *transmembrane protein ,...
Semi thesaurus term： topology ,...

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JST classification (3)： Transport of cell membrane  (EF04020R) ,  Gene expression  (EC02040Q) ,  Biological function  (EB03040U)

Substance index (2)： N-Ethylmaleimide ,  AMS

Reference (25)：

• 1. Ma, D., Cook, D. N., Albert, M., Pon, N. G., Nikaido, H., and Hearst, J. E. (1993) Molecular cloning and characterization of acrA and acrE genes of Escherichia coli. J Bacteriol. 175, 6299-6313
• 2. Kawabe, T., Fujihira, E., and Yamaguchi, A. (2000) Molecular construction of a multidrug exporter system, AcrAB: molecular interaction between AcrA and AcrB, and cleavage of the N-terminal signal sequence of AcrA. J. Biochem. 128, 195-200
• 3. Dinh T., Paulsen, I. T, and Saier, Jr. M. H. (1994) A family of extracytoplasmic proteins that allow transport of large molecules across the outer membranes of gram-negative bacteria J. Bacteriol. 176, 3825-3831
• 4. Saier Jr, M. H., Tam, R., Reizer, A., and Reizer J. (1994) Two novel families of bacterial membrane proteins concerned with nodulation. cell division and transport. Mol. Microbiol 11. 841-847
• 5. Okusu, H., Ma, D., and Nikaido, H. (1996) AcrAB efflux pump plays a major role in the antibiotic resistance phenotype of Escherichia coli multiple-antibiotic-resistance (Mar) mutants. J. Bacteriol. 178, 306-308

Terms in the title (4)： 大腸菌 ,  輸送体 ,  AcrB ,  膜トポロジー