Art

J-GLOBAL ID：200902171971038862   Reference number：01A0478640

Biological Evaluation of the Pollution of Rivers Flowing into Tokyo Bay with the 7-Ethoxycoumarin O-deethylase(ECOD) Activity Induced by River Sediment Extracts in HepG2 Cells.

HepG2細胞における河川堆積物抽出物により誘発された7-エトキシクマリン O-デエチラーゼ(ECOD)活性を用いた東京湾流入河川の汚染の生物学的評価

Author (5)： NITO S (Toho Univ., Chiba, JPN) ,  TODOROKI N (Toho Univ., Chiba, JPN) ,  MISUMI M (Toho Univ., Chiba, JPN) ,  NAKAHAMA T (Toho Univ., Chiba, JPN) ,  INOUYE Y (Toho Univ., Chiba, JPN)
Material： Journal of Health Science  (J Health Sci)
Volume： 47  Issue： 2  Page： 118-122  Publication year： Apr. 01, 2001 
JST Material Number： S0030A  ISSN： 1344-9702  CODEN： JHSCFD  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： polynuclear aromatic hydrocarbon ,...
Semi thesaurus term： *ethoxycoumarin deethylase ,...

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JST classification (3)： River pollution  (SB02020F) ,  Bioassay  (EA03060N) ,  Enzyme in general  (EB09010D)

Substance index (1)： 7-Ethoxycoumarin

Reference (9)：

• 1) Nakama, A., Yoshikura, T. and Fukunaga, I. (1997) Induction of cytochrome P450 in Hep G2 cells and mutagenicity of extracts of sedeiment from a waste disposal site near Osaka, Japan. Bull. Environ. Contam. Toxicol., 59, 344-351.
• 2) Papoulias, D.M., Buckler, D.R. and Tillitt, D.E. (1996) Optimization of the Ames/Salmonella mutagenicity assay for use with extracts of aquatic sediments. J. Great Lakes Research, 22, 584-590.
• 3) Jarvis, A.S., Honeycutt, M.E., McFarland, V.A., Bulich, A.A. and Bounds, H.C. (1996) A comparison of the Ames assay and mutatox in assessing the mutagenic potential of contaminated dredged sediment. Ecotoxicology & Environmental Safety, 33, 193-200.
• 4) Ho, K.T., Miills, L.J., Mueller, C., Anderson, S.C. and Malcolm, A.R. (1994) The influence of sediment extract fractionation methods on bioassay results. Environmental Toxicology & Water Quality, 9, 145-154.
• 5) Till, M., Riebniger, D., Schmitz, H-J. and Schrenk, D. (1999) Potency of various polycyclic aromatic hydrocarbons as inducers of CYP1A1 in rat hepatocyte cultures. Chemico-Biological Interactions, 117, 135-150.

Terms in the title (10)： HepG2細胞 ,  河川堆積物 ,  抽出物 ,  誘発 ,  7-エトキシクマリン ,  活性 ,  東京湾 ,  流入河川 ,  汚染 ,  生物学的評価