Art

J-GLOBAL ID：200902172633743379   Reference number：00A0665949

Effect of the p53 gene on synchronization of cells with hydroxyurea and on the cell phase response to hyperthermia in vitro.

ヒドロキシ尿素による細胞周期同調および各細胞周期位相における温熱感受性に及ぼすp53遺伝子の影響

Author (7)： HATASHITA M (Fukui Medical Univ., Fukui, JPN) ,  KANO E (Fukui Medical Univ., Fukui, JPN) ,  HAYASHI S (Fukui Medical Univ., Fukui, JPN) ,  MATSUMOTO H (Fukui Medical Univ., Fukui, JPN) ,  OHTSUBO T (Fukui Medical Univ., Fukui, JPN) ,  JIN Z-H (Fukui Medical Univ., Fukui, JPN) ,  ITOH H (Fukui Medical Univ., Fukui, JPN)
Material： 日本ハイパーサーミア学会誌  (Japanese Journal of Hyperthermic Oncology)
Volume： 16  Issue： 2  Page： 107-115  Publication year： Jun. 2000 
JST Material Number： L0930A  ISSN： 0911-2529  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *p53 gene ,...
Semi thesaurus term： 温熱感受性

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JST classification (1)： Chemistry,biochemistry and pathology of tumors(=neoplasms)  (GE02030N)

Substance index (1)： Hydroxycarbamide

Reference (24)：

• WESTRA, A. Variation in sensitivity to heat shock during the cell-cycle of Chinese hamster cells in vitro. Int J Radiat Biol Relat Stud Phys Chem Med. 1971, 19, 467-477
• DEWEY, W. C. Heat-induced lethality and chromosomal damage in synchronized Chinese hamster cells treated with 5-bromodeoxyuridine. Int J Radiat Biol Relat Stud Phys Chem Med. 1971, 20, 505-520
• SUZUKI, K. Differences in effects of oncogenes on resistance of gamma rays, ultraviolet light, and heat shock. Radiat Res. 1992, 129, 157-162
• MATSUMOTO, H. Transfection of p53-knockout mouse fibroblasts with wild-type p53 increases the thermosensitivity and stimulates apoptosis induced by heat stress. Int J Radiat Oncol Biol Phys. 1997, 39, 197-203
• HAYASHI, S. Thermosensitivity, incidence of apoptosis and accumulations of hsp72 and p53 proteins of murine L cells in wild type status of p53 gene. J Exp Clin Cancer Res. 1999, 18, 181-189

Terms in the title (7)： ヒドロキシ尿素 ,  細胞周期 ,  同調 ,  位相 ,  温熱 ,  感受性 ,  p53遺伝子