Art

J-GLOBAL ID：200902172644898102   Reference number：01A0468061

Regulation of Endothelial Nitric Oxide Synthase and Endothelin-1 Expression by Fluvastatin in Human Vascular Endothelial Cells.

ヒト血管内皮細胞における内皮型一酸化窒素シンターゼ及びエンドセリン1の発現のフルバスタチンによる調節

Author (6)： OZAKI K (Niigata Univ. School of Medicine, Niigata, JPN) ,  YAMAMOTO T (Niigata Univ. School of Medicine, Niigata, JPN) ,  ISHIBASHI T (Kanazawa Medical Univ., Ishikawa, JPN) ,  MATSUBARA T (Niigata Univ. School of Medicine, Niigata, JPN) ,  NISHIO M (Kanazawa Medical Univ., Ishikawa, JPN) ,  AIZAWA Y (Niigata Univ. School of Medicine, Niigata, JPN)
Material： Japanese Journal of Pharmacology  (Jpn J Pharmacol)
Volume： 85  Issue： 2  Page： 147-154  Publication year： Feb. 01, 2001 
JST Material Number： G0813A  ISSN： 0021-5198  CODEN： JJPAA  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： human(primates) ,...
Semi thesaurus term： 内皮型一酸化窒素シンターゼ

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JST classification (2)： Basic research of drugs acting on lipid metabolism  (GW13040M) ,  Basic research of enzyme preparations and enzyme inhibitor preparations  (GW21010W)

Substance index (2)： Fluvastatin ,  Endothelin-1

Reference (36)：

• 1 Vane JR, Anggard EE and Botting RM: Regulatory functions of the vascular endothelium. N Engl J Med 323, 27 - 36 (1990)
• 2 Cooke JP, Singer AH, Tsao P, Zera P, Rowan RA and Billingham ME: Antiatherogenic effects of L-arginine in the hypercholesterolemic rabbit. J Clin Invest 90, 1168 - 1172 (1992)
• 3 Creager MA, Gallagher SJ, Girerd XJ, Coleman SM, Dzau VJ and Cooke JP: L-Arginine improves endothelium-dependent vasodilation in hypercholesterolemic humans. J Clin Invest 90, 1248 - 1253 (1992)
• 4 Kowala MC: The role of endothelin in the pathogenesis of atherosclerosis. Adv Pharmacol 37, 299 - 318 (1997)
• 5 Harrison DG, Armstrong ML, Freiman PC and Heistad DD: Restoration of endothelium-dependent relaxation by dietary treatment of atherosclerosis. J Clin Invest 80, 1808 - 1811 (1987)

Terms in the title (7)： ヒト ,  血管内皮細胞 ,  内皮型一酸化窒素シンターゼ ,  エンドセリン1 ,  発現 ,  フルバスタチン ,  調節