Art

J-GLOBAL ID：200902173509354050   Reference number：98A0544433

Enzymatic Peptide Synthesis with p-Guanidinophenyl and p-(Guanidinomethyl)phenyl Esters as Acyl Donors.

アシルドナーとしてp-グアニジノフェニル及びp-(グアニジノメチル)フェニルエステルを用いた酵素的ペプチド合成

Author (4)： SEKIZAKI H (Health Sci. Univ. Hokkaido, Hokkaido, JPN) ,  ITOH K (Health Sci. Univ. Hokkaido, Hokkaido, JPN) ,  TOYOTA E (Health Sci. Univ. Hokkaido, Hokkaido, JPN) ,  TANIZAWA K (Health Sci. Univ. Hokkaido, Hokkaido, JPN)
Material： Chemical and Pharmaceutical Bulletin  (Chemical & Pharmaceutical Bulletin)
Volume： 46  Issue： 5  Page： 846-849  Publication year： May. 1998 
JST Material Number： G0504A  ISSN： 0009-2363  CODEN： CPBTAL  Document type： Article
Article type： 短報  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： chemical synthesis ,...
Semi thesaurus term： *guanidines ,...

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JST classification (3)： Peptides  (CF10080G) ,  Aromatic monocyclic ureas,carbamic acids,guanidines  (CF05220O) ,  Applications of enzymes  (EB09100B)

Substance index (14)： Boc-L-Ala-OGp ,  Boc-D-Ala-OGp ,  N-(tert-Butoxycarbonyl)-β-alanine 4-guanidinophenyl ester ,  2-(tert-Butyloxycarbonylamino)isobutyric acid 4-guanidinophenyl ester ,  N-(tert-Butoxycarbonyl)-L-alanine 4-(guanidinomethyl)phenyl ester ,  N-(tert-Butoxycarbonyl)-D-alanine 4-(guanidinomethyl)phenyl ester ,  N-(tert-Butoxycarbonyl)-β-alanine 4-(guanidinomethyl)phenyl ester ,  2-(tert-Butyloxycarbonylamino)isobutyric acid 4-(guanidinomethyl)phenyl ester ,  Boc-L-Ala-L-Ala-4-Nitrophenyl NH₂ ,  Boc-D-Ala-L-Ala-(4-Nitrophenyl)NH₂ ,  Boc-βAla-L-Ala-Nan ,  Boc-Aib-L-Ala-4-Nitrophenyl NH₂ ,  Boc-L-Ala-D-Ala-Nan ,  Boc-D-Ala-D-Ala-Nan

Reference (18)：

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• Nakatuka T., Sasaki T., Kaiser E.T., J. Am. Chem. Soc., 99, 4485-4488 (1987)
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• Schellenberger V., Jakubke H.-D., Angew. Chem. Int. Ed. Engl., 30, 1437-1449 (1991).
• 3) Itoh K., Sekizaki H., Toyota E., Tanizawa K., Chem. Pharm. Bull., 43, 2082-2087 (1995).

Terms in the title (2)： 酵素 ,  ペプチド合成