Art

J-GLOBAL ID：200902174132510326   Reference number：98A0605165

Efficient Induction of Hepatocyte Spheroids in a Suspension Culture Using a Water-Soluble Synthetic Polymer as an Artificial Matrix.

人工マトリックスとして水溶性合成ポリマーを用いる懸濁培養における肝細胞スフェロイドの効率的誘導

Author (4)： YAMADA K (Nagoya Univ., Nagoya) ,  KAMIHIRA M (Nagoya Univ., Nagoya) ,  HAMAMOTO R (Nagoya Univ., Nagoya) ,  IIJIMA S (Nagoya Univ., Nagoya)
Material： Journal of Biochemistry  (J Biochem)
Volume： 123  Issue： 6  Page： 1017-1023  Publication year： Jun. 1998 
JST Material Number： F0286A  ISSN： 0021-924X  CODEN： JOBIAO  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *artificial liver ,...
Semi thesaurus term： Eudragit ,...

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JST classification (1)： Prosthesis(=artificial substitutes for body part)  (EL04000N)

Reference (30)：

• GUMBINER, B. M. Cell adhesion: The molecular basis of tissue architecture and morphogenesis. Cell. 1996, 84, 345-357
• BEN-ZE'EV, A. Cell-cell and cell-matrix interactions differentially regulate the expression of hepatic and cytoskeletal genes in primary cultures of rat hepatocytes. Proc. Natl. Acad. Sci. USA. 1988, 85, 2161-2165
• HANSEN, L. K. Integrin binding and cell spreading on extracellular matrix act at different points in the cell cycle to promote hepatocyte growth. Mol. Biol. Cell. 1994, 5, 967-975
• BISSELL, D. M. Support of cultured hepatocytes by a laminin-rich gel. J. Clin. Invest. 1987, 79, 801-812
• DUNN, J. C. Long-term in vitro function of adult hepatocytes in a collagen sandwich configuration. Biotechnol. Prog. 1991, 7, 237-245

Terms in the title (7)： 人工 ,  マトリックス ,  水溶性 ,  合成ポリマー ,  懸濁培養 ,  細胞スフェロイド ,  誘導