Art

J-GLOBAL ID：200902174923497579   Reference number：96A0753982

Synthesis and Tryptic Hydrolysis of p-Guanidinophenyl Esters Derived from Amino Acids and Peptides.

アミノ酸及びペプチドから誘導したp-グアニジノフェニルエステルの合成とトリプシンによる加水分解

Author (4)： SEKIZAKI H (Health Sci. Univ. Hokkaido, Hokkaido, JPN) ,  ITOH K (Health Sci. Univ. Hokkaido, Hokkaido, JPN) ,  TOYOTA E (Health Sci. Univ. Hokkaido, Hokkaido, JPN) ,  TANIZAWA K (Health Sci. Univ. Hokkaido, Hokkaido, JPN)
Material： Chemical and Pharmaceutical Bulletin  (Chemical & Pharmaceutical Bulletin)
Volume： 44  Issue： 8  Page： 1577-1579  Publication year： Aug. 1996 
JST Material Number： G0504A  ISSN： 0009-2363  CODEN： CPBTAL  Document type： Article
Article type： 短報  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： Trypsin ,...
Semi thesaurus term： guanidines ,...

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JST classification (2)： Peptides  (CF10080G) ,  Enzyme in general  (EB09010D)

Substance index (14)： N-(tert-Butoxycarbonyl)glycine 4-[2,3-bis(benzyloxycarbonyl)guanidino]phenyl ester ,  N-(tert-Butoxycarbonyl)-L-alanine 4-[2,3-bis(benzyloxycarbonyl)guanidino]phenyl ester ,  N-(tert-Butoxycarbonyl)-D-alanine 4-[2,3-bis(benzyloxycarbonyl)guanidino]phenyl ester ,  N-(tert-Butoxycarbonyl)-L-leucine 4-[2,3-bis(benzyloxycarbonyl)guanidino]phenyl ester ,  N-(tert-Butoxycarbonyl)-D-leucine 4-[2,3-bis(benzyloxycarbonyl)guanidino]phenyl ester ,  N-(tert-Butoxycarbonyl)-L-phenylalanine 4-[2,3-bis(benzyloxycarbonyl)guanidino]phenyl ester ,  N-(tert-Butoxycarbonyl)-D-phenylalanine 4-[2,3-bis(benzyloxycarbonyl)guanidino]phenyl ester ,  N-(tert-Butoxycarbonyl)-β-alanine 4-[2,3-bis(benzyloxycarbonyl)guanidino]phenyl ester ,  Boc-Gly-Gly-[4-[2,3-Bis(benzyloxycarbonyl)guanidino]phenyl]OH ,  Boc-Gly-Gly-Gly-[4-[2,3-Bis(benzyloxycarbonyl)guanidino]phenyl]OH ,  Boc-L-Ala-Gly-[4-[2,3-Bis(benzyloxycarbonyl)guanidino]phenyl]OH ,  Boc-D-Ala-Gly-[4-[2,3-Bis(benzyloxycarbonyl)guanidino]phenyl]OH ,  Boc-L-Phe-L-Phe-[4-[2,3-Bis(benzyloxycarbonyl)guanidino]phenyl]OH ,  Boc-L-Tyr-Gly-Gly-L-Phe-[4-[2,3-Bis(benzyloxycarbonyl)guanidino]phenyl]OH

Reference (16)：

• NOZAWA, M. J. Pharmacobio-Dyn. 1980, 3, 213-219
• TANIZAWA, K. J. Am. Chem. Soc. 1977, 99, 4485-4488
• ITOH, K. Bioorg. Chem. 1996, 24, 59-68
• SCHELLENBERGER, V. Biotechnol. Bioeng. 1991, 38, 104-108
• SCHELLENBERGER, V. Biotechnol. Bioeng. 1991, 38, 319-321

Terms in the title (5)： アミノ酸 ,  ペプチド ,  誘導 ,  トリプシン ,  加水分解