Art
J-GLOBAL ID：200902176099987653   Reference number：00A0069420

Complex Target-Oriented Synthesis in the Drug Discovery Process: A Case History in the dEpoB Series.

医薬品の発見過程における複雑な分子を標的とした有機合成 dEpoB系化合物における事例史
Author (2)：
HARRIS C R

About HARRIS C R

(Sloan-Kettering Inst. Cancer Res., New York)

About Sloan-Kettering Inst. Cancer Res., New York

, 
DANISHEFSKY S J

About DANISHEFSKY S J

(Sloan-Kettering Inst. Cancer Res., New York)

About Sloan-Kettering Inst. Cancer Res., New York


Material：
Journal of Organic Chemistry  (J Org Chem)

About Journal of Organic Chemistry


Volume： 64  Issue： 23  Page： 8434-8456  Publication year： Nov. 12, 1999 
JST Material Number： C0328A  ISSN： 0022-3263  CODEN： JOCEAH  Document type： Article
Article type： 文献レビュー  Country of issue： United States (USA)  Language： ENGLISH (EN)
Thesaurus term：
Thesaurus term/Semi thesaurus term
Keywords indexed to the article.
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chemical synthesis

About chemical synthesis

,...
Semi thesaurus term：
Thesaurus term/Semi thesaurus term
Keywords indexed to the article.
All keywords is available on JDreamIII(charged).
On J-GLOBAL, this item will be available after more than half a year after the record posted. In addtion, medical articles require to login to MyJ-GLOBAL.
*cytotoxin

About cytotoxin

,...
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JST classification (2)：
JST classification
Category name(code) classified by JST.
Eight or more-membered heterocyclic compounds 
(CF07120T)

About Eight or more-membered heterocyclic compounds

,  Synthesis of drugs 
(GV01030F)

About Synthesis of drugs

Substance index (3)：
Substance index
Chemical Substance indexed to the Article.
(1S,3S,7S,10R,11S,12S,16R)-7,11-Dihydroxy-8,8,10,12-tetramethyl-3-[1-methyl-2-(2-methyl-4-thiazolyl)ethenyl]-4,17-dioxabicyclo[14.1.0]heptadecane-5,9-dione

About (1S,3S,7S,10R,11S,12S,16R)-7,11-Dihydroxy-8,8,10,12-tetramethyl-3-[1-methyl-2-(2-methyl-4-thiazolyl)ethenyl]-4,17-dioxabicyclo[14.1.0]heptadecane-5,9-dione

, 
(4S,7R,8S,9S,13R,14S,16S)-13,14-Epoxy-4,8-dihydroxy-5,5,7,9,13-pentamethyl-16-[1-methyl-2-(2-methyl-4-thiazolyl)ethenyl]oxacyclohexadecane-2,6-dione

About (4S,7R,8S,9S,13R,14S,16S)-13,14-Epoxy-4,8-dihydroxy-5,5,7,9,13-pentamethyl-16-[1-methyl-2-(2-methyl-4-thiazolyl)ethenyl]oxacyclohexadecane-2,6-dione

, 
Epothilone D

About Epothilone D

Terms in the title (7)：
Terms in the title
Keywords automatically extracted from the title.
医薬品

About 医薬品

, 
発見

About 発見

, 
過程

About 過程

, 
分子

About 分子

, 
標的

About 標的

, 
有機合成

About 有機合成

, 
事例史

About 事例史


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