Art

J-GLOBAL ID：200902179524181314   Reference number：02A0462130

Catalysis-Linked Inactivation of Fluoroacetate Dehalogenase by Ammonia: A Novel Approach to Probe the Active-Site Environment.

アンモニアによるフルオロ酢酸デハロゲナーゼの触媒付随失活 活性部位環境を探るための新しいアプローチ

Author (7)： ICHIYAMA S (Kyoto Univ., Kyoto) ,  KURIHARA T (Kyoto Univ., Kyoto) ,  MIYAGI M (Takara Shuzo Co., Ltd., Shiga) ,  GALKIN A (Kyoto Univ., Kyoto) ,  TSUNASAWA S (Takara Shuzo Co., Ltd., Shiga) ,  KAWASAKI H (Univ. Osaka Prefecture, Osaka) ,  ESAKI N (Kyoto Univ., Kyoto)
Material： Journal of Biochemistry  (J Biochem)
Volume： 131  Issue： 5  Page： 671-677  Publication year： May. 01, 2002 
JST Material Number： F0286A  ISSN： 0021-924X  CODEN： JOBIAO  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： Ammonia ,...
Semi thesaurus term： Moraxella ,...

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JST classification (1)： Enzyme in general  (EB09010D)

Substance index (1)： Fluoroacetic acid

Reference (22)：

• 1. Kawasaki, H., Yahara, H., and Tonomura, K. (1984) Cloning and expression in Escherichia coli of the haloacetate dehaloge-nase genes from Moraxella plasmid pUO1. Agric. Biol. Chem. 48, 2627-2632
• 2. Liu, J. -Q., Kurihara, T, Hasan, A. K. M. Q., Nardi-Dei, V., Koshikawa, H., Esaki, N., and Soda, K. (1994) Purification and characterization of thermostable and nonthermostable 2-halo-acid dehalogenases with different stereospecificities from Pseudomonas sp. strain YL. Appl. Enuiron. Microbiol. 60, 2389-2393
• 3. Liu, J. -Q., Kurihara, T, Miyagi, M., Esaki, N., and Soda, K. (1995) Reaction mechanism of L-2-haloacid dehalogenase of Pseudomonas sp. YL. Identification of Asp¹⁰ as the active site nucleophile by ¹⁸O incorporation experiments. J. Biol. Chem. 270, 18309-18312
• 4. Liu, J. -Q., Kurihara, T., Ichiyama, S., Miyagi, M., Tsunasawa, S., Kawasaki, H., Soda, K., and Esaki, N. (1998) Reaction mech-anism of fluoroacetate dehalogenase from Moraxella sp. B. J. Biol. Chem. 273, 30897-30902
• 5. Nardi-Dei, V., Kurihara, T., Okamura, T., Liu, J. -Q., Koshikawa, H., Ozaki, H., Terashima, Y., Esaki, N., and Soda, K. (1994) Comparative studies of genes encoding thermostable L-2-halo acid dehalogenase from Pseudomonas sp. strain YL, other de-halogenases, and two related hypothetical proteins from Escherichia coll. Appl. Environ. Microbial. 60, 3375-3380

Terms in the title (7)： アンモニア ,  フルオロ酢酸 ,  デハロゲナーゼ ,  触媒 ,  失活 ,  活性部位 ,  環境