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J-GLOBAL ID：200902179709519168   Reference number：96A0703765

Inhibition by Adrenomedullin of Arginine Vasopressin-Activated Mitogen-Activated Protein Kinase in Rat Glomerular Mesangial Cells via cAMP Production.

cAMPを産生を介するラット腎臓糸球体メサンギウム細胞におけるアルギニンバソプレシン活性化ミトゲン活性化蛋白キナーゼのアドレノメデュリンによる抑制

Author (7)： KUSAKA I (Jichi Medical School, Tochigi, JPN) ,  ISHIKAWA S (Jichi Medical School, Tochigi, JPN) ,  FUJITA N (Jichi Medical School, Tochigi, JPN) ,  HIGASHIYAMA M (Jichi Medical School, Tochigi, JPN) ,  HONDA K (Jichi Medical School, Tochigi, JPN) ,  OKADA K (Jichi Medical School, Tochigi, JPN) ,  SAITO T (Jichi Medical School, Tochigi, JPN)
Material： Hypertension Research, Clinical and Experimental  (Hypertens Res Clin Exp)
Volume： 19  Issue： 2  Page： 113-119  Publication year： Jun. 1996 
JST Material Number： Y0303A  ISSN： 0916-9636  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： mesangium cell ,...
Semi thesaurus term： アドレノメデュリン ,...

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JST classification (1)： Basic medicine on urogenital system  (GM01020T)

Reference (28)：

• 1). Kitamura K, Kangawa K, Kawamoto M, et al: Adrenomedullin: a novel hypotensive peptide isolated from human pheochromocytoma. Biochem Biophys Res Commun 1993; 192: 553-560.
• 2). Sugo S, Minamino N, Shoji H, et al: Production and secretion of adrenomedullin from vascular smooth muscle cells: augmented production by tumor necrosis factor-α. Biochem Biophys Res Commun 1994; 203: 719-726.
• 3). Eguchi S, Hirata Y, Iwasaki H, et al: Structure-activity relationship of adrenomedullin, a novel vasodilatory peptide, in cultured rat vascular smooth muscle cells. Endocrinology 1994; 135: 2454-2458.
• 4). Eguchi S, Hirata Y, Kano H, et al: Specific receptors for adrenomedullin in cultured rat vascular smooth muscle cells. FEBS Lett 1994; 340: 226-230.
• 5). Ishizaka Y, Ishizaka Y, Tanaka M, et al: Adrenomedullin stimulates cyclic AMP formation in rat vascular smooth muscle cells. Biochem Biophys Res Commun 1994; 200: 642-646.

Terms in the title (8)： cAMP ,  ラット ,  腎臓糸球体 ,  メサンギウム細胞 ,  アルギニンバソプレシン ,  活性化 ,  蛋白キナーゼ ,  アドレノメデュリン