Art

J-GLOBAL ID：200902180174011788   Reference number：99A0864602

Effects of Missense Mutations Phe110Ile and Glu244Asp in Human Cardiac Troponin T on Force Generation in Skinned Cardiac Muscle Fibers.

心筋スキンドファイバーの張力発生に及ぼすヒト心筋トロポニンTミスセンス変異Phe110IleとGlu244Aspの影響

Author (4)： NAKAURA H (Kyushu Univ., Fukuoka) ,  YANAGA F (Kyushu Univ., Fukuoka) ,  OHTSUKI I (Kyushu Univ., Fukuoka) ,  MORIMOTO S (Kyushu Univ., Fukuoka)
Material： Journal of Biochemistry  (J Biochem)
Volume： 126  Issue： 3  Page： 457-460  Publication year： Sep. 01, 1999 
JST Material Number： F0286A  ISSN： 0021-924X  CODEN： JOBIAO  Document type： Article
Article type： 短報  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *Troponin ,...

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JST classification (3)： Biological function  (EB03040U) ,  Heart  (EJ04020D) ,  Cardiovascular system diseases  (GJ03000C)

Reference (17)：

• EBASHI, S. Calcium ion and muscle contrac-tion. Prog, Biophys. Mol. Biol. 1968, 18, 123-183
• OHTSUKI, I. Regulatory and cytoskeletal proteins of vertebrate skeletal muscle. Adu. Protein Chem. 1986, 38, 1-67
• PERRY, S. V. Troponin T: genetics, properties and function. J. Muscle Res. Cell Motil. 1998, 19, 575-602
• MORIMOTO, S. Ca^<2+>-sensitizing effects of the mutations at Ile-79 and Arg-92 of troponin T in hypertrophic cardiomyopathy. Am. J. Physiol. 1998, 275, C200-C207
• MORIMOTO, S. Functional consequences of a carboxyl terminal missense muta-tion Arg278Cys in human cardiac troponin T. Biochem. Biophys. Res. Commun. 1999, 261, 79-82

Terms in the title (5)： 心筋 ,  張力 ,  ヒト ,  心筋トロポニンT ,  ミスセンス変異