Art

J-GLOBAL ID：200902182292676673   Reference number：99A0709150

Antiproliferative Activity of Flavonoids on Several Cancer Cell Lines.

数種のがん細胞に対するフラボノイド類の細胞増殖抑制活性

Author (5)： KAWAII S (National Inst. Fruit Tree Sci., Shizuoka, JPN) ,  TOMONO Y (National Inst. Fruit Tree Sci., Shizuoka, JPN) ,  KATASE E (National Inst. Fruit Tree Sci., Shizuoka, JPN) ,  OGAWA K (National Inst. Fruit Tree Sci., Shizuoka, JPN) ,  YANO M (National Inst. Fruit Tree Sci., Shizuoka, JPN)
Material： Bioscience, Biotechnology, and Biochemistry  (Bioscience Biotechnology & Biochemistry)
Volume： 63  Issue： 5  Page： 896-899  Publication year： May. 23, 1999 
JST Material Number： G0021A  ISSN： 0916-8451  CODEN： BBBIEJ  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *flavonoid ,...

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JST classification (2)： Fruits and processed fruit products  (FJ11030Z) ,  Chemistry,biochemistry and pathology of tumors(=neoplasms)  (GE02030N)

Substance index (27)： Eriodictyol ,  Hesperidin ,  Hesperetin ,  Naringenin ,  Naringin ,  Taxifolin ,  Acacetin ,  Apigenin ,  Diosmin ,  Kaempferol ,  Luteolin ,  Rutin ,  Quercetin ,  Eriocitrin ,  Neoeriocitrin ,  Neohesperidin ,  Didymin ,  Narirutin ,  Poncirin ,  Isorhoifolin ,  Neodiosmin ,  Rhoifolin ,  Heptamethoxyflavone ,  Nobiletin ,  Natsudaidain ,  Sinensetin ,  Tangeretin

Reference (20)：

• 1) Deschner, E. E., Ruperto, J., Wong, G., and Newmark, H. L., Quercetin and rutin as inhibitors of azoxymethanol-induced colonic neoplasia. Carcinogenesis, 12, 1193-1196 (1991).
• 2) Hirano, T., Abe, K., Gotoh, M., and Oka, K., Citrus flavone tangeretin inhibits leukaemic HL-60 cell growth partially through induction of apoptosis with less cytotoxicity on normal lymphocytes. Br. J. Cancer, 72, 1380-1388 (1995).
• 3) So, F. V., Guthrie, N., Chambers, A. F., Moussa, M., and Carroll, K. K., Inhibition of human breast cancer cell proliferation and delay of mammary tumorigenesis by flavonoids and citrus juices. Nutr. Cancer, 26, 167-181 (1996).
• 4) Benavente-García, O., Castillo, J., Marin, F. R., Ortuño, A., and Del Río, J. A., Use and properties of Citrus flavonoids. J. Agric. Food Chem., 45, 4506-4515 (1997).
• 5) Murakami, A., Kuki, W., Takahashi, Y., Yonei, H., Nakamura, Y., Ohto, Y., Ohigashi, H., and Koshimizu, K., Auraptene, a citrus coumarin, inhibits 12-O-tetradecanoylphorbol-13-acetate-induced tumor promotion in ICR mouse skin, possibly through suppression of superoxide generation in leukocytes. Jpn. J. Cancer Res., 88, 443-452 (1997).

Terms in the title (3)： がん細胞 ,  フラボノイド類 ,  細胞増殖抑制活性