Art

J-GLOBAL ID：200902182773448577   Reference number：03A0113307

Inactivation of Cardiac Na⁺ Channel Simply through Open States as Revealed by Single-Channel Analysis in Guinea Pig Ventricular Myocytes.

モルモット心室筋細胞の単一チャネル解析により判明した開口状態時のみの心臓Na⁺チャネルの不活性化

Author (2)： MITSUIYE T (Kyoto Univ., Kyoto, JPN) ,  NOMA A (Kyoto Univ., Kyoto, JPN)
Material： Japanese Journal of Physiology  (Jpn J Physiol)
Volume： 52  Issue： 5  Page： 457-469  Publication year： Oct. 2002 
JST Material Number： Z0753A  ISSN： 0021-521X  CODEN： JJPHAM  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： guinea pig ,...
Semi thesaurus term： myocyte

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JST classification (2)： Transport of cell membrane  (EF04020R) ,  Heart  (EJ04020D)

Reference (35)：

• 1. Marban E, Yamagishi T, and Tomaselli GF: Structure and function of voltage-gated sodium channels. J Physiol (Lond) 508: 647-657, 1998
• 2. Stuhmer W, Conti F, Suzuki H, Wang X, Noda M, Yahagi N, Kubo H, and Numa S: Structural parts involved in activation and inactivation of the sodium channel. Nature 339: 597-603, 1989
• 3. Moorman JR, Kirch GE, Brown AM, and Joho RH: Changes in sodium channel gating produced by point mutations in a cytoplasmic linker. Science 250: 688-691, 1990
• 4. Hartmann HA, Tiedeman AA, Chen SF, Brown AM, and Kirsch GE: Effects of III-IV linker mutations on human heart Na⁺ channel inactivation gating. Circ Res 75: 114-22, 1994
• 5. McPhee JC, Ragsdale DS, Scheuer T, and Catterall WA: A critical role for the S4-S5 intracellular loop in domain IV of the sodium channel alpha-subunit in fast inactivation. J Biol Chem 273: 1121-1129, 1998

Terms in the title (7)： モルモット ,  心室筋細胞 ,  チャネル ,  解析 ,  心臓 ,  Na+チャネル ,  不活性化