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J-GLOBAL ID：200902183885503933   Reference number：97A0529413

Solid Phase Synthesis of Fused Bicyclic Amino Acid Derivatives via Intramolecular Pauson-Khand Cyclization: Versatile Scaffolds for Combinatorial Chemistry.

分子内Pauson-Khand環化を経る縮合二環アミノ酸誘導体の固相合成 コンビナトリアルケミストリー用の応用自在な骨格化合物

Author (3)： BOLTON G L (Parke-Davis Pharmaceutical Res., MI) ,  HODGES J C (Parke-Davis Pharmaceutical Res., MI) ,  RUBIN J R (Parke-Davis Pharmaceutical Res., MI)
Material： Tetrahedron  (Tetrahedron Symposia-in-Print)
Volume： 53  Issue： 19  Page： 6611-6634  Publication year： May. 12, 1997 
JST Material Number： E0234A  ISSN： 0040-4020  Document type： Article
Article type： 原著論文  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Thesaurus term： chemical synthesis ,...
Semi thesaurus term： コンビナトリアルライブラリー ,...

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JST classification (2)： Other condensed derivatives of pyridine  (CF07097Y) ,  Amino acids  (CF10070V)

Substance index (17)： (3S)-2-Tosyl-5-phenyl-6-oxo-2,3,4,6,7,7aβ-hexahydro-1H-2-pyrindine-3α-carboxylic acid methyl ester ,  (1S,4S)-3-Tosyl-8-oxo-3-azabicyclo[4.3.0]non-6-ene-4α-carboxylic acid methyl ester ,  (4S,6S)-3-Tosyl-8-oxo-9-phenyl-3-azabicyclo[4.3.0]non-9(1)-ene-4α-carboxylic acid methyl ester ,  (4S,6S)-3-Tosyl-8-oxo-3-azabicyclo[4.3.0]non-9(1)-ene-4α-carboxylic acid methyl ester ,  (3S)-2-Tosyl-5-(4-methoxyphenyl)-6-oxo-2,3,4,6,7,7aβ-hexahydro-1H-2-pyrindine-3α-carboxylic acid methyl ester ,  (3S)-2-Tosyl-5-(4-chlorophenyl)-6-oxo-2,3,4,6,7,7aβ-hexahydro-1H-2-pyrindine-3α-carboxylic acid methyl ester ,  (3S)-2-Tosyl-5-[4-(methoxycarbonyl)phenyl]-6-oxo-2,3,4,6,7,7aβ-hexahydro-1H-2-pyrindine-3α-carboxylic acid methyl ester ,  (3S)-2-Tosyl-6-oxo-7-(4-methoxyphenyl)-2,3,4,4aα,5,6-hexahydro-1H-2-pyrindine-3α-carboxylic acid methyl ester ,  (3S)-2-Tosyl-6-oxo-7-(4-chlorophenyl)-2,3,4,4aα,5,6-hexahydro-1H-2-pyrindine-3α-carboxylic acid methyl ester ,  (3S)-2-Tosyl-6-oxo-7-[4-(methoxycarbonyl)phenyl]-2,3,4,4aα,5,6-hexahydro-1H-2-pyrindine-3α-carboxylic acid methyl ester ,  (3S)-2-Tosyl-6-oxo-7β-phenyl-2,3,4,6,7,7aβ-hexahydro-1H-2-pyrindine-3-carboxylic acid methyl ester ,  (3S)-2-(2-Nitrophenylsulfonyl)-6-oxo-2,3,4,6,7,7aβ-hexahydro-1H-2-pyrindine-3α-carboxylic acid methyl ester ,  (3S)-2-(2-Aminophenylsulfonyl)-6-oxo-2,3,4,6,7,7aβ-hexahydro-1H-2-pyrindine-3α-carboxylic acid methyl ester ,  (3S,4aα,7aα)-2-Tosyl-6α-(methylbenzoylamino)octahydro-1H-2-pyrindine-3α-carboxylic acid methyl ester ,  (3S,4aα,7aα)-2-Tosyl-6β-(methylbenzoylamino)octahydro-1H-2-pyrindine-3α-carboxylic acid methyl ester ,  (3S,4aα,7aα)-2-Tosyl-6α-(acetylbenzylamino)octahydro-1H-2-pyrindine-3α-carboxylic acid methyl ester ,  (3S,4aα,7aα)-2-Tosyl-6β-(acetylbenzylamino)octahydro-1H-2-pyrindine-3α-carboxylic acid methyl ester

Terms in the title (8)： 環化 ,  縮合 ,  二環 ,  アミノ酸誘導体 ,  固相合成 ,  コンビナトリアルケミストリー ,  応用 ,  骨格