Art

J-GLOBAL ID：200902185680860566   Reference number：02A0417164

Investigation of Intracellular Factors Involved in Methylmercury Toxicity.

メチル水銀毒性に関与する細胞内因子の検討

Author (5)： NAGANUMA A (Tohoku Univ., Sendai) ,  FURUCHI T (Tohoku Univ., Sendai) ,  MIURA N (Tohoku Univ., Sendai) ,  HWANG G-W (Tohoku Univ., Sendai) ,  KUGE S (Tohoku Univ., Sendai)
Material： Tohoku Journal of Experimental Medicine  (Tohoku J Exp Med)
Volume： 196  Issue： 2  Page： 65-70  Publication year： Feb. 2002 
JST Material Number： G0649A  ISSN： 0040-8727  CODEN： TJEMAO  Document type： Article
Article type： 文献レビュー  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *Mercury Poisoning ,...
Semi thesaurus term： *cell physiology ,...

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JST classification (1)： Toxicity of metals and metal compounds  (GZ02022V)

Reference (23)：

• Akagi, H. & Naganuma, A. (2000) Human exposure to mercury and the accumulation of methylmercury that is associated with gold mining in the Amazon basin, Brazil. J. Health Sci., 46, 323-328.
• Furuchi, T., Hwang, G.W. & Naganuma, A. (2002) Overexpression of the ubiquitin-conjugating enzyme Cdc34 confers resistance to methymercury is Saccharomyces cerevisiae. Mol. Pharmacol. (in press)
• Hershko, A. & Ciechanover, A. (1998) The ubiquitin system. Annu. Rev. Biochem., 67, 425-479.
• Hochstrasser, M. (1996) Ubiquitination-dependent protein degradation. Annu. Rev. Genet., 30, 405-439.
• Hwang, G.W., Furuchi, T. & Naganuma, A. (2002) A ubiquitin-proteasome system is responsible for the protection of yeast and human cells against methylemercury. FASEB J. (in press)

Terms in the title (4)： メチル水銀 ,  毒性 ,  細胞 ,  内因子