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J-GLOBAL ID：200902186110710869   Reference number：02A0673497

α-Glucosidase Inhibitory Activity of a 70% Methanol Extract from Ezoishige (Pelvetia babingtonii de Toni) and Its Effect on the Elevation of Blood Glucose Level in Rats.

エゾイシゲ(Pelvetia babingtonii)からの70%メタノール抽出物のα-グルコシダーゼ阻害活性ならびにラットにおける血中グルコース濃度の上昇に及ぼすその抽出物の影響

Author (5)： OHTA T (Hokkaido Food Processing Res. Center, Hokkaido, JPN) ,  SASAKI S (Hokkaido Food Processing Res. Center, Hokkaido, JPN) ,  OOHORI T (Hokkaido Food Processing Res. Center, Hokkaido, JPN) ,  YOSHIKAWA S (Hokkaido Food Processing Res. Center, Hokkaido, JPN) ,  KURIHARA H (Hokkaido Univ., Hokkaido, JPN)
Material： Bioscience, Biotechnology, and Biochemistry  (Bioscience Biotechnology & Biochemistry)
Volume： 66  Issue： 7  Page： 1552-1554  Publication year： Jul. 23, 2002 
JST Material Number： G0021A  ISSN： 0916-8451  CODEN： BBBIEJ  Document type： Article
Article type： 短報  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： Phaeophyceae ,...
Semi thesaurus term： glycoside hydrolase ,...

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JST classification (3)： Marine algae(=seaweeds)  (FJ13030N) ,  Enzyme in general  (EB09010D) ,  Metabolism and nutrition of sugar(=glucide)  (EJ02035H)

Substance index (3)： Methanol ,  Sucrose ,  Glucose

Reference (10)：

• 1) Schmidt, D. D., Frommer, W., Junge, B., Muller, L., Wingender, E., Trushelt, E., and Schafer, D., α-Glucosidase inhibitors. Naturwissenschften, 64, 535-536 (1977).
• 2) Horii, S., Fukase, H., Matsuo, T., Kameda, Y., Asano, N., and Matsui, K., Synthesis and α-glucosidase inhibitory activity of N-substituted valiolamine derivatives as potential oral antidiabetic agents. J. Med. Chem., 29, 1038-1046 (1987).
• 3) Nishioka, T., Kawabata, J., and Aoyama, Y., Baicalein, an α-glucosidase inhibitor from Scutellaria baicalensis. J. Nat. Prod., 61, 1413-1415 (1998).
• 4) Kurihara, H., Ando, J., Hatano, M., and Kawabata, J., Sulfoquinovosyldiacylglycerol as an α-glucosidase inhibitor. Bioorg. Med. Chem. Lett., 61, 263-266 (1997).
• 5) Watanabe, J., Kawabata, J., and Niki, R., Isolation and identification of α-glucosidase inhibitors from tochu-cha (Eucommia ulmoides). Biosci. Biotechnol. Biochem., 61, 177-178 (1997).

Terms in the title (6)： メタノール抽出物 ,  α-グルコシダーゼ ,  阻害活性 ,  ラット ,  血中グルコース ,  抽出物