Art

J-GLOBAL ID：200902186949735506   Reference number：97A0548507

New Ulcerative Colitis Model Induced by Sulfhydryl Blockers in Rats and the Effects of Antiinflammatory Drugs on the Colitis.

ラットにおけるスルフヒドリル阻害薬によって誘発される新規潰よう性結腸炎モデル及びこの結腸炎に対する抗炎症薬の影響

Author (4)： SATOH H (Takeda Chemical Ind. Ltd., Osaka, JPN) ,  SATO F (Takeda Chemical Ind. Ltd., Osaka, JPN) ,  TAKAMI K (Takeda Chemical Ind. Ltd., Osaka, JPN) ,  SZABO S (Harvard Medical School, Massachusetts, USA)
Material： Japanese Journal of Pharmacology  (Jpn J Pharmacol)
Volume： 73  Issue： 4  Page： 299-309  Publication year： Apr. 1997 
JST Material Number： G0813A  ISSN： 0021-5198  CODEN： JJPAA  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： colitis (colon) ,...
Semi thesaurus term： iodoacetamide ,...

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JST classification (2)： Basic research of anti-inflammatory drugs  (GW15010T) ,  Basic medicine on digestive system  (GH01020E)

Substance index (6)： N-Ethylmaleimide ,  Iodoacetamide ,  Indomethacin ,  Dinoprostone ,  AA-861 ,  Dexamethasone

Reference (42)：

• 1 Beeken WL: Experimental inflammatory bowel disease. In Inflammatory Bowel Disease, Edited by Kirsner JB and Shorter RG, pp 37-49, Lea & Febiger, Philadelphia (1988)
• 2 Elson CO: The immunology of inflammatory bowel disease. In Inflammatory Bowel Disease, Edited by Kirsner JB and Shorter RG, pp 97-164, Lea & Febiger, Philadelphia (1988)
• 3 Szabo S, Trier JS and Frankel PW: Sulfhydryl compounds may mediate gastric cytoprotection. Science 214, 200-202 (1981)
• 4 Szabo S, Pihan G and Dupuy D: The biochemical pharmacology of sulfhydryl compounds in gastric mucosal injury and protection. In New Pharmacology of Ulcer Disease, Edited by Szabo S and Mozsik G, pp 425-436, Elsevier Science Publishing (1988)
• 5 Krawisz JE, Sharon P and Stenson WF: Quantitative assay for acute intestinal inflammation based on myeloperoxidase activity. Gastroenterology 87, 1344-1350 (1984)

Terms in the title (7)： ラット ,  阻害薬 ,  誘発 ,  潰よう性結腸炎 ,  モデル ,  結腸炎 ,  抗炎症薬