Art

J-GLOBAL ID：200902188474857620   Reference number：00A0514027

Identification and Characterization of a Deletion Mutant of DNA Topoisomerase I mRNA in a Camptothecin-resistant Subline of Human Colon Carcinoma.

ヒト結腸癌細胞のカンプトテシン抵抗性株におけるDNAトポイソメラーゼ1mRNA欠失変異の同定と特性指摘

Author (6)： YANASE K (Japanese Foundation for Cancer Res., Tokyo) ,  SUGIMOTO Y (Japanese Foundation for Cancer Res., Tokyo) ,  TSUKAHARA S (Japanese Foundation for Cancer Res., Tokyo) ,  OH-HARA T (Japanese Foundation for Cancer Res., Tokyo) ,  ANDOH T (Soka Univ., Tokyo) ,  TSURUO T (Japanese Foundation for Cancer Res., Tokyo)
Material： Japanese Journal of Cancer Research  (Proceedings. Annual Meeting of the Japanese Cancer Association)
Volume： 91  Issue： 5  Page： 551-559  Publication year： May. 31, 2000 
JST Material Number： F0633A  ISSN： 0910-5050  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： human(primates) ,...

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JST classification (1)： Basic research of antitumor(=antineoplastic)drugs  (GW16010A)

Substance index (1)： Camptothecin

Reference (47)：

• GOTTLIEB, J. A. Preliminary pharmacologic and clinical evaluation of camptothecin sodium (NSC 100880). Cancer Chemother. Rep. 1970, 54, 461-470
• GOTTLIEB, J. A. Treatment of malignant melanoma with camptothecin (NSC-100880). Cancer Chemother. Rep. 1972, 56, 103-105
• MOERTEL, C. G. Phase II study of camptothecin (NSC-100880) in the treatment of advanced gastrointestinal cancer. Cancer Chemother. Rep. 1972, 56, 95-101
• MUGGIA, F. M. Phase I clinical trial of weekly and daily treatment with camptothecin (NSC-100880); correlation with preclinical studies. Cancer Chemother. Rep. 1972, 56, 515-521
• SCHAEPPI, U. Toxicity of camptothecin (NSC-100880). Cancer Chemother. Rep. Part 3. 1974, 5, 25-36

Terms in the title (8)： ヒト ,  結腸癌 ,  細胞 ,  カンプトテシン ,  抵抗性 ,  株 ,  欠失変異 ,  同定