Art

J-GLOBAL ID：200902190355831898   Reference number：00A0257220

In vitro Antitumor Activity, Intracellular Accumulation, and DNA Adduct Formation of cis-[((1R,2R)-1,2-Cyclohexanediamine-N,N′)bis(myristato)]Platinum(II) Suspended in Lipiodol.

リピオドールに懸濁したcis-[((1R,2R)-1,2-シクロヘキサンジアミン-N,N’)ビス(ミリスタト)]白金(II)のin vitro抗腫よう活性,細胞内蓄積およびDNA付加物形成

Author (4)： KISHIMOTO S (Kobe Gakuin Univ., Kobe) ,  MIYAZAWA K (Kobe Gakuin Univ., Kobe) ,  FUKUSHIMA S (Kobe Gakuin Univ., Kobe) ,  TAKEUCHI Y (Kobe Gakuin Univ., Kobe)
Material： Japanese Journal of Cancer Research  (Proceedings. Annual Meeting of the Japanese Cancer Association)
Volume： 91  Issue： 1  Page： 99-104  Publication year： Jan. 31, 2000 
JST Material Number： F0633A  ISSN： 0910-5050  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *antitumor drug ,...
Semi thesaurus term： lipiodol ,...

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JST classification (2)： Basic research of antitumor(=antineoplastic)drugs  (GW16010A) ,  Basic biopharmacy  (GY01021U)

Reference (16)：

• MINOYAMA, A. Study of repeated arterial infusion chemotherapy with a subcutaneously implanted reservoir for advanced hepatocellular carcinoma. J. Gastroenterol. 1995, 30, 356-366
• ROUGIER, P. Intra-arterial hepatic chemotherapy with pirarubicin. Preclinical and clinical studies. Am. J. Clin. Oncol. 1990, 13, S1-S4
• VEXLER, A. M. Reduction of the systemic toxicity of cisplatin by intra-arterial hepatic route administration for liver malignancies. Int. J. Cancer. 1995, 60, 611-615
• IWAI, K. Use of oily contrast medium for selective drug targeting to tumor : enhanced therapeutic effect and X-ray image. Cancer Res. 1984, 44, 2115-2121
• KONNO, T. Targeting cancer chemotherapeutic agents by use of lipiodol contrast medium. Cancer. 1990, 66, 1897-1903

Terms in the title (8)： リピオドール ,  懸濁 ,  CIS ,  ビス ,  白金 ,  抗腫よう活性 ,  細胞内蓄積 ,  DNA付加物