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J-GLOBAL ID：200902193796996638   Reference number：99A0864607

Human Subtilisin-Like Proprotein Convertase, PACE4 (SPC4) Gene Expression Is Highly Regulated through E-Box Elements in HepG2 and GH4C1 Cells.

ヒトスブチリシン様前駆体蛋白質変換酵素PACE4(SPC4)の遺伝子はHepG2とGH4C1細胞でE-ボックスエレメントを介して高度に制御される

Author (8)： TSUJI A (Univ. Tokushima, Tokushima) ,  YOSHIDA S (Univ. Tokushima, Tokushima) ,  HASEGAWA S (Univ. Tokushima, Tokushima) ,  BANDO M (Univ. Tokushima, Tokushima) ,  YOSHIDA I (Univ. Tokushima, Tokushima) ,  KOIDE S (Univ. Tokushima, Tokushima) ,  MORI K (Univ. Tokushima, Tokushima) ,  MATSUDA Y (Univ. Tokushima, Tokushima)
Material： Journal of Biochemistry  (J Biochem)
Volume： 126  Issue： 3  Page： 494-502  Publication year： Sep. 01, 1999 
JST Material Number： F0286A  ISSN： 0021-924X  CODEN： JOBIAO  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： human(primates) ,...
Semi thesaurus term： *subtilisin ,...

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JST classification (2)： Gene expression  (EC02040Q) ,  Enzyme in general  (EB09010D)

Reference (55)：

• SEIDAH, N. G. The family of subtilisin/kexin like pro-protein and pro-hormone convertases: Divergent or shared funtions. Biochimie. 1994, 76, 197-209
• NAKAYAMA, K. Furin: a mammalian subtilisin/Kex2p-like endoprotease involved in processing of a wide variety of precursor proteins. Biochem. J. 1997, 327, 625-635
• SMMEKENS, S. P. Identification of a human insulinoma cDNA encoding a novel mammalian protein structurally related to the yeast dibasic processing protease Kex2. J. Biol. Chem. 1990, 265, 2997-3000
• SMEEKENS, S. P. Identification of a cDNA encoding a second putative prohormone convertase related to PC2 in AtT20 cells and islets of Langerhans. Proc. Natl. Acad. Sci. USA. 1991, 88, 340-344
• KIEFER, M. C. Identification of a second human subtilisin-like protease gene in the fes/fps region of chromosome 15. DNA Cell Biol. 1991, 10, 757-769

Terms in the title (11)： ヒト ,  スブチリシン ,  前駆体 ,  蛋白質 ,  酵素 ,  PACE4 ,  遺伝子 ,  HepG2 ,  GH4C1細胞 ,  E-ボックス ,  エレメント