Art

J-GLOBAL ID：200902194777079019   Reference number：01A0888913

Antitumor Activity of Antisense Clusterin Oligonucleotides Is Improved in Vitro and in Vivo by Incorporation of 2′-O-(2-Methoxy)Ethyl Chemistry.

アンチセンスクラステリンオリゴヌクレオチドの抗腫よう活性は2′-O-(2-メトキシ)エチル結合によりin vitroとin vivoで増大する

Author (7)： ZELLWEGER T (Prostate Centre at Vancouver General Hospital, British Columbia) ,  MIYAKE H (Prostate Centre at Vancouver General Hospital, British Columbia) ,  COOPER S (ISIS Pharmaceuticals, California, CAN) ,  CHI K (Prostate Centre at Vancouver General Hospital, British Columbia) ,  CONKLIN B S (ISIS Pharmaceuticals, California, CAN) ,  MONIA B P (ISIS Pharmaceuticals, California, CAN) ,  GLEAVE M E (Prostate Centre at Vancouver General Hospital, British Columbia)
Material： Journal of Pharmacology and Experimental Therapeutics  (J Pharmacol Exp Ther)
Volume： 298  Issue： 3  Page： 934-940  Publication year： Sep. 2001 
JST Material Number： E0052A  ISSN： 0022-3565  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Thesaurus term： *glycoprotein ,...
Semi thesaurus term： bridged compound

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JST classification (2)： Basic research of antitumor(=antineoplastic)drugs  (GW16010A) ,  Gene manipulation  (EC02050B)

Substance index (1)： Paclitaxel

Terms in the title (1)： 抗腫よう活性