Art

J-GLOBAL ID：200902195995992091   Reference number：01A0862364

The Effect of 1,3-Diaryl-[1H]-pyrazole-4-acetamides on Glucose Utilization in ob/ob Mice.

ob/obマウスでのグルコース利用に及ぼす1,3-ジアリール-[1H]-ピラゾール-4-アセトアミド類の効果

Author (9)： BEBERNITZ G R (Novartis Pharmaceuticals Corp., New Jersey) ,  ARGENTIERI G (Novartis Pharmaceuticals Corp., New Jersey) ,  BATTLE B (Novartis Pharmaceuticals Corp., New Jersey) ,  BRENNAN C (Novartis Pharmaceuticals Corp., New Jersey) ,  BALKAN B (Novartis Pharmaceuticals Corp., New Jersey) ,  BURKEY B F (Novartis Pharmaceuticals Corp., New Jersey) ,  ECKHARDT M (Novartis Pharmaceuticals Corp., New Jersey) ,  GAO J (Novartis Pharmaceuticals Corp., New Jersey) ,  XU D D (Novartis Pharmaceuticals Corp., New Jersey)
Material： Journal of Medicinal Chemistry  (J Med Chem)
Volume： 44  Issue： 16  Page： 2601-2611  Publication year： Aug. 02, 2001 
JST Material Number： D0102A  ISSN： 0022-2623  CODEN： JMCMAR  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Thesaurus term： nitrogen heterocyclic compound ,...
Semi thesaurus term： insulin

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JST classification (2)： Basic research of drugs acting on carbohydrate metabolism  (GW13020Q) ,  Pyrazoles  (CF07082G)

Substance index (26)： 3-Phenyl-1-[3-(trifluoromethyl)phenyl]-N,N-dimethyl-1H-pyrazole-4-acetamide ,  1-[3-(Trifluoromethyl)phenyl]-3-(3,4-dichlorophenyl)-N,N-dimethyl-1H-pyrazole-4-acetamide ,  1-(3-Fluorophenyl)-3-(3,4-dichlorophenyl)-N,N-dimethyl-1H-pyrazole-4-acetamide ,  1-(3-Nitrophenyl)-3-(3,4-dichlorophenyl)-N,N-dimethyl-1H-pyrazole-4-acetamide ,  1-(4-Methoxyphenyl)-3-(3,4-dichlorophenyl)-N,N-dimethyl-1H-pyrazole-4-acetamide ,  1-(4-Chlorophenyl)-3-(3,4-dichlorophenyl)-N,N-dimethyl-1H-pyrazole-4-acetamide ,  1-(4-Fluorophenyl)-3-(3,4-dichlorophenyl)-N,N-dimethyl-1H-pyrazole-4-acetamide ,  1-[4-(Trifluoromethyl)phenyl]-3-(3,4-dichlorophenyl)-N,N-dimethyl-1H-pyrazole-4-acetamide ,  1-(3,4-Dichlorophenyl)-3-(3,4-dichlorophenyl)-N,N-dimethyl-1H-pyrazole-4-acetamide ,  3-(p-Tolyl)-1-[3-(trifluoromethyl)phenyl]-N,N-dimethyl-1H-pyrazole-4-acetamide ,  3-(4-Biphenylyl)-1-[3-(trifluoromethyl)phenyl]-N,N-dimethyl-1H-pyrazole-4-acetamide ,  3-(9H-Fluorene-2-yl)-1-[3-(trifluoromethyl)phenyl]-N,N-dimethyl-1H-pyrazole-4-acetamide ,  3-(9,9-Dimethyl-9H-fluorene-2-yl)-1-[3-(trifluoromethyl)phenyl]-N,N-dimethyl-1H-pyrazole-4-acetamide ,  3-(9-Acetoxy-9H-fluorene-2-yl)-1-[3-(trifluoromethyl)phenyl]-N,N-dimethyl-1H-pyrazole-4-acetamide ,  3-(9-Hydroxy-9-methyl-9H-fluorene-2-yl)-1-[3-(trifluoromethyl)phenyl]-N,N-dimethyl-1H-pyrazole-4-acetamide ,  3-(9-Oxo-9H-fluorene-2-yl)-1-[3-(trifluoromethyl)phenyl]-N,N-dimethyl-1H-pyrazole-4-acetamide ,  3-(9H-Xanthene-2-yl)-1-[3-(trifluoromethyl)phenyl]-N,N-dimethyl-1H-pyrazole-4-acetamide ,  3-(Dibenzothiophene-2-yl)-1-[3-(trifluoromethyl)phenyl]-N,N-dimethyl-1H-pyrazole-4-acetamide ,  3-(Phenanthrene-2-yl)-1-[3-(trifluoromethyl)phenyl]-N,N-dimethyl-1H-pyrazole-4-acetamide ,  3-(9,10-Dihydroanthracene-2-yl)-1-[3-(trifluoromethyl)phenyl]-N,N-dimethyl-1H-pyrazole-4-acetamide ,  3-(3,4-Dichlorophenyl)-1-[3-(trifluoromethyl)phenyl]-1H-pyrazole-4-acetic acid ,  3-(3,4-Dichlorophenyl)-1-[3-(trifluoromethyl)phenyl]-N,N-diethyl-1H-pyrazole-4-acetamide ,  3-(3,4-Dichlorophenyl)-1-[3-(trifluoromethyl)phenyl]-N,N-tetramethylene-1H-pyrazole-4-acetamide ,  3-(3,4-Dichlorophenyl)-1-[3-(trifluoromethyl)phenyl]-1H-pyrazole-4-acetic acid ethyl ester ,  3-(3,4-Dichlorophenyl)-1-[3-(trifluoromethyl)phenyl]-N-methoxy-1H-pyrazole-4-acetamide ,  3-(3,4-Dichlorophenyl)-1-[3-(trifluoromethyl)phenyl]-N,N-dibenzyl-1H-pyrazole-4-acetamide

Terms in the title (4)： マウス ,  グルコース利用 ,  ピラゾール ,  アセトアミド類