Art

J-GLOBAL ID：200902196233136208   Reference number：98A0723634

Isotope Dilution Analysis for Urinary Fentanyl and Its Main Metabolite, Norfentanyl, in Patients by Isotopic Fractionation Using Capillary Gas Chromatography.

キャピラリガスクロマトグラフィを用いた同位体希釈分析による患者尿中フェンタニルおよび主代謝物ノルフェンタニルの定量

Author (5)： SERA S (Fukuyama Univ., Hiroshima Pref., JPN) ,  GOROMARU T (Fukuyama Univ., Hiroshima Pref., JPN) ,  SAMESHIMA T (Kagoshima Univ. School of Medicine, Kagoshima Pref., JPN) ,  KAWASAKI K (Kagoshima Univ. School of Medicine, Kagoshima Pref., JPN) ,  ODA T (Kagoshima Univ. School of Medicine, Kagoshima Pref., JPN)
Material： Radioisotopes
Volume： 47  Issue： 7  Page： 537-545  Publication year： Jul. 1998 
JST Material Number： G0494A  ISSN： 0033-8303  CODEN： RAISAB  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *isotope dilution analysis ,...
Semi thesaurus term： *fentanyl

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JST classification (2)： Radiochemical analysis of organic compounds  (CC06034V) ,  Basic research of psychotropic drugs  (GW03100Y)

Reference (23)：

• YOSHIMURA, S. Identification of fentanyl metabolites in rat urine by gas chromatography-mass spectrometry with stable-isotope tracers. Drug metab. Dispos. 1982, 10, 542-546
• GOROMARU, T. Identification and quantitative determination of fentanyl metabolites in patients by gas chromatography-mass spectrometry. Anesthesiology. 1984, 61, 73-77
• GOROMARU, T. Metabolism of fentanyl in isolated hepatocytes from rat and guinea pig. Chem. Pharm. Bull. 1985, 33, 3922-3928
• GOROMARU, T. Urinary excretion of fentanyl and its metabolites at high-dose infusion. Masui. 1986, 35, 35-39
• GOROMARU, T. Isotopic fractionation of iproniazid and isopropylhydrazine from their deuterated analogues and application for isotope dilution analysis by capillary gas chromatography. Yakugaku Zasshi. 1991, 111, 612-616

Terms in the title (7)： 同位体希釈分析 ,  患者 ,  尿 ,  フェンタニル ,  代謝物 ,  ノルフェンタニル ,  定量