Art

J-GLOBAL ID：200902197168488335   Reference number：00A0416597

Chimeric Glycosaminoglycan Oligosaccharides Synthesized by Enzymatic Reconstruction and Their Use in Substrate Specificity Determination of Streptococcus Hyaluronidase.

酵素的再構築により合成したキメラキメグリコサミノグリカン少糖類及びそのStreptococcusヒアルロニダーゼの特異性決定への使用

Author (5)： TAKAGI K (Hirosaki Univ. School of Medicine, Hirosaki) ,  MUNAKATA H (Hirosaki Univ. School of Medicine, Hirosaki) ,  MAJIMA M (Kushiro Junior Coll., Kushiro) ,  KAKIZAKI I (Hirosaki Univ. School of Medicine, Hirosaki) ,  ENDO M (Hirosaki Univ. School of Medicine, Hirosaki)
Material： Journal of Biochemistry  (J Biochem)
Volume： 127  Issue： 4  Page： 695-702  Publication year： Apr. 01, 2000 
JST Material Number： F0286A  ISSN： 0021-924X  CODEN： JOBIAO  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： enzymatic synthesis ,...
Semi thesaurus term： *hyaluronidase ,...

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JST classification (2)： Carbohydrates and sugar chains in general  (EB06010I) ,  Enzyme in general  (EB09010D)

Substance index (1)： N-Acetylgalactosamine

Reference (42)：

• CHOAY, J. Structure-activity relationship in heparin: a synthetic pentasaccharide with high affinity for antithrombin III and eliciting high anti-factor Xa activity. Biochem. Biophys. Res. Commun. 1983, 116, 492-499
• van BOECKL, C. A. A. Synthesis of a pentasaccharide corresponding to the antithrombin III binding fragment of heparin. J. Carbohydr. Chem. 1985, 4, 293-321
• ICHIKAWA, Y. Synthesis of a heparin pentasaccharide fragment with a high affinity for antithrombin III employing cellobiose as a key starting material. Tetrahedron, Lett. 1986, 27, 611-614
• GOTO, F. Recent aspects of glycoconjugate synthesis: a synthetic approach to the linkage region of proteoglycans. Pure. Appl. Chem. 1993, 65, 973-801
• TOONE, E. J. Enzyme-catalyzed synthesis of carbohydrates. Tetrahedron. 1989, 45, 5365-5422

Terms in the title (6)： 酵素 ,  再構築 ,  少糖類 ,  Streptococcus ,  ヒアルロニダーゼ ,  特異性