Art

J-GLOBAL ID：200902197496812417   Reference number：01A0078075

New Potential Antimalarial Agents. Synthesis and Biological Activities of Original Diaza-analogs of Phenanthrene.

新しい潜在的抗マラリア薬 独創的なフェナントレンジアザ類似体の合成及び生物活性

Author (8)： YAPI A D (Fac. Pharmacie, Montpellier, FRA) ,  MUSTOFA M (Univ. Gadjah Mada, Yogyakarta, IDN) ,  VALENTIN A (Univ. Gadjah Mada, Yogyakarta, IDN) ,  CHAVIGNON O (UFR de Pharmacie, Clermont-Ferrand, FRA) ,  TEULADE J-C (UFR de Pharmacie, Clermont-Ferrand, FRA) ,  MALLIE M (Univ. Gadjah Mada, Yogyakarta, IDN) ,  CHAPAT J-P (Fac. Pharmacie, Montpellier, FRA) ,  BLACHE Y (Fac. Pharmacie, Montpellier, FRA)
Material： Chemical and Pharmaceutical Bulletin  (Chemical & Pharmaceutical Bulletin)
Volume： 48  Issue： 12  Page： 1886-1889  Publication year： Dec. 01, 2000 
JST Material Number： G0504A  ISSN： 0009-2363  CODEN： CPBTAL  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *nitrogen heterocyclic compound ,...

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JST classification (2)： Other condensed derivatives of pyridine  (CF07097Y) ,  Synthesis of drugs  (GV01030F)

Substance index (20)： Halofantrine ,  Pyronaridine ,  3-Aminoquinoline ,  5-Aminoquinoline ,  6-Aminoquinoline ,  8-Aminoquinoline ,  3-[1-(3-Quinolinylamino)ethylidene]tetrahydrofuran-2-one ,  3-[1-(5-Quinolinylamino)ethylidene]tetrahydrofuran-2-one ,  3-[1-(6-Quinolinylamino)ethylidene]tetrahydrofuran-2-one ,  3-[1-(8-Quinolinylamino)ethylidene]tetrahydrofuran-2-one ,  5-Aminoisoquinoline ,  3-[1-(5-Isoquinolinylamino)ethylidene]tetrahydrofuran-2-one ,  1-Chloro-2-(2-chloroethyl)-3-methylbenzo[f][1,7]naphthyridine ,  2-Methyl-3-(2-chloroethyl)-4-chloro-1,7-phenanthroline ,  1-Chloro-2-(2-chloroethyl)-3-methyl-4,7-phenanthroline ,  2-Methyl-3-(2-chloroethyl)-4-chloro-1,10-phenanthroline ,  2-Methyl-3-(2-chloroethyl)-4-chloro-1,8-phenanthroline ,  2,10-Dimethyl-3-(2-chloroethyl)-4-chloro-1,10-phenanthroline-10-ium ,  2,10-Dimethyl-3-(2-chloroethyl)-4-chloro-1,10-phenanthroline-10-ium・iodide ,  2-Methyl-3-(2-chloroethyl)-4-chloro-1,10-phenanthroline・hydrochloride

Reference (17)：

• BLACHE, Y. Tetrahedron. 1999, 55, 1959-1970
• BLACHE, Y. J.Org.Chem. 1997, 62, 8553-8556
• BLACHE, Y. Heterocycles. 1997, 45, 57-69
• CHEZAL, J. M. J.Org.Chem. 1997, 62, 4085-4087
• CASTEDO, L. The Alkaloids. 1990, 39, 99-138

Terms in the title (3)： 抗マラリア薬 ,  類似体 ,  生物活性