Art

J-GLOBAL ID：200902200309401191   Reference number：09A0291375

New Aspects for the Treatment of Cardiac Diseases Based on the Diversity of Functional Controls on Cardiac Muscles: Effects of Targeted Disruption of the Type 5 Adenylyl Cyclase Gene

心筋機能コントロールの多様性に基づく心疾患治療の新しい側面:5型アデニル酸シクラーゼ遺伝子の標的破壊の影響

Author (4)： OKUMURA Satoshi (Cardiovascular Res. Inst., Yokohama City Univ. Graduate School of Medicine, JPN) ,  SUZUKI Sayaka (Cardiovascular Res. Inst., Yokohama City Univ. Graduate School of Medicine, JPN) ,  ISHIKAWA Yoshihiro (Cardiovascular Res. Inst., Yokohama City Univ. Graduate School of Medicine, JPN) ,  ISHIKAWA Yoshihiro (Cardiovascular Res. Inst., Dep. of Cell Biology & Molecular Medicine and Medicine (Cardiology), New Jersey Medical ...)
Material： Journal of Pharmacological Sciences  (J Pharmacol Sci)
Volume： 109  Issue： 3  Page： 354-359 (J-STAGE)  Publication year： 2009 
JST Material Number： G0813A  ISSN： 1347-8613  Document type： Article
Article type： 解説  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： control ,...
Semi thesaurus term： *心筋機能コントロール ,...

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JST classification (1)： Basic medicine on cardiovascular system  (GJ01020K)

Substance index (1)： cAMP

Reference (23)：

• TAUSSIG, R. Mammalian membrane-bound adenylyl cyclases. J Biol Chem. 1995, 270, 1-4
• SCOTT, JD. Cyclic nucleotide-dependent protein kinases. Pharmacol Ther. 1991, 50, 123-145
• HANOUNE, J. Regulation and role of adenylyl cyclase isoforms. Annu Rev Pharmacol Toxicol. 2001, 41, 145-174
• ISHIKAWA, Y. The adenylyl cyclases as integrators of transmembrane signal transduction. Circ Res. 1997, 80, 297-304
• ISHIKAWA, Y. Isolation and characterization of a novel cardiac adenylylcyclase cDNA. J Biol Chem. 1992, 267, 13553-13557

Terms in the title (9)： 心筋機能 ,  コントロール ,  多様性 ,  心疾患 ,  治療 ,  アデニル酸シクラーゼ ,  遺伝子 ,  標的 ,  破壊