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J-GLOBAL ID：200902200311743741   Reference number：09A0733481

The significance of podoplanin expression in human inflamed gingiva

ヒトの炎症歯肉におけるポドプラニン発現の意味

Author (12)： MIYAZAKI Yuji (Div. of Pathology, Dep. of Diagnostic and Therapeutic Sciences, Meikai Univ. School of Dentistry) ,  OKAMOTO Eri (Second Div. of Oral and Maxillofacial Surgery, Dep. of Diagnostic and Therapeutic Sciences, Meikai Univ. School of ...) ,  GONZALEZ-ALVA Patricia (Div. of Pathology, Dep. of Diagnostic and Therapeutic Sciences, Meikai Univ. School of Dentistry) ,  HAYASHI Joichiro (Div. of Periodontology, Dep. of Oral Biology and Tissue Engineering, Meikai Univ. School of Dentistry) ,  ISHIGE Toshiyuki (Dep. of Pathology, Nihon Univ. School of Medicine) ,  KIKUCHI Kentaro (Div. of Pathology, Dep. of Diagnostic and Therapeutic Sciences, Meikai Univ. School of Dentistry) ,  KIKUCHI Kentaro (Dep. of Pathology, Nihon Univ. School of Medicine) ,  NEMOTO Norimichi (Dep. of Pathology, Nihon Univ. School of Medicine) ,  SHIN Kitetsu (Div. of Periodontology, Dep. of Oral Biology and Tissue Engineering, Meikai Univ. School of Dentistry) ,  SAKASHITA Hideaki (Second Div. of Oral and Maxillofacial Surgery, Dep. of Diagnostic and Therapeutic Sciences, Meikai Univ. School of ...) ,  OCHIAI Kuniyasu (Dep. of Microbiology, Nihon Univ. School of Dentistry) ,  KUSAMA Kaoru (Div. of Pathology, Dep. of Diagnostic and Therapeutic Sciences, Meikai Univ. School of Dentistry)
Material： Journal of Oral Science  (J Oral Sci)
Volume： 51  Issue： 2  Page： 283-287 (J-STAGE)  Publication year： 2009 
JST Material Number： Z0759A  ISSN： 1343-4934  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： oncoprotein ,...
Semi thesaurus term： podoplanin ,...

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JST classification (1)： Basic dentistry(= odontology)  (GT01020O)

Reference (23)：

• 1. Pihlstrom BL, Michalowicz BS, Johnson NW (2005) Periodontal diseases. Lancet 366, 1809-1820.
• 2. Schacht V, Ramirez MI, Hong YK, Hirakawa S, Feng D, Harvey N, Williams M, Dvorak AM, Dvorak HF, Oliver G, Detmar M (2003) T1α/podoplanin deficiency disrupts normal lymphatic vasculature formation and causes lymphedema. EMBO J 22, 3546-3556.
• 3. Schacht V, Dadras SS, Johnson LA, Jackson DG, Hong YK, Detmar M (2005) Up-regulation of the lymphatic marker podoplanin, a mucin-type transmembrane glycoprotein, in human squamous cell carcinomas and germ cell tumors. Am J Pathol 166, 913-921.
• 4. Martín-Villar E, Megías D, Castel S, Yurrita MM, Vilaró S, Quintanilla M (2006) Podoplanin binds ERM proteins to activate RhoA and promote epithelial-mesenchymal transition. J Cell Sci 119, 4541-4553.
• 5. Wicki A, Lehembre F, Wick N, Hantusch B, Kerjaschki D, Christofori G (2006) Tumor invasion in the absence of epithelial-mesenchymal transition: podoplanin-mediated remodeling of the actin cytoskeleton. Cancer Cell 9, 261-272.

Terms in the title (6)： ヒト ,  炎症 ,  歯肉 ,  ポドプラニン ,  発現 ,  意味