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J-GLOBAL ID：200902200411019803   Reference number：06A0743147

Effects of Bifemelane on the Calcium Level and ATP Release of the Human Origin Astrocyte Clonal Cell

ヒト由来アストロサイトクローン細胞のCaレベル及びATP放出に対するビフェメランの影響

Author (7)： YOSHIDA Yoshitoku (School of Life Sci., Tokyo Univ. of Pharmacy and Life Sci., JPN) ,  KUMAGAI Haruno (School of Life Sci., Tokyo Univ. of Pharmacy and Life Sci., JPN) ,  OHKUBO Yoshiumi (School of Life Sci., Tokyo Univ. of Pharmacy and Life Sci., JPN) ,  TSUCHIYA Remi (School of Life Sci., Tokyo Univ. of Pharmacy and Life Sci., JPN) ,  MORITA Mitsuhiro (School of Life Sci., Tokyo Univ. of Pharmacy and Life Sci., JPN) ,  MIYAKAWA Hiroyoshi (School of Life Sci., Tokyo Univ. of Pharmacy and Life Sci., JPN) ,  KUDO Yoshihisa (School of Life Sci., Tokyo Univ. of Pharmacy and Life Sci., JPN)
Material： Journal of Pharmacological Sciences  (J Pharmacol Sci)
Volume： 102  Issue： 1  Page： 121-128 (J-STAGE)  Publication year： 2006 
JST Material Number： G0813A  ISSN： 1347-8613  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： human(primates) ,...
Semi thesaurus term： calcium channel blocker ,...

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JST classification (1)： Basic research of psychotropic drugs  (GW03100Y)

Substance index (5)： adenosine triphosphate ,  Bifemelane ,  Inositol 1,4,5-Trisphosphate ,  Bifemelan hydrochloride ,  2-APB

Reference (23)：

• 1 Haydon PG. Glia: listening and talking to the synapse. Nat Rev Neurosci. 2001;2:185–193.
• 2 ChaoTI, Rickmann M, Wolff JR. The synapse-astrocyte boundary: anatomical basis for an integrative role of glia in synaptic transmission. In: Volterra A, Magistretti P, Haydon P, editors. Tripertite synapses: synaptic transmission with glia. Oxford, New York, Oxford University Press; 2002. p. 3–23.
• 3 Nedergaard M, Ransom BR, Goldmann S. New roles for astorcytes: Redefining the functional architecture of the brain. Trends Neurosci. 2003;26:523–530.
• 4 Araque A, Sanzgiri RP, Parpura V, Haydon PG. Glutamate-dependent astrocyte modulation of synaptic transmission. Can J Physiol Pharamcol. 1999;77:699–706.
• 5 Yoshida Y, Nakane A, Morita M, Kudo Y. A novel effect of bifemelane, a nootropic drug, on intracelluar Ca²⁺ levels in rat cerebral astrocytes. J Pharmacol Sci. 2006;100:126–132.

Terms in the title (7)： ヒト ,  アストロサイト ,  クローン細胞 ,  Ca ,  ATP ,  放出 ,  ビフェメラン