Art

J-GLOBAL ID：200902201386335351   Reference number：04A0806099

A Synthetic Polymer, Poly(2-methacryloyloxyethyl phosphorylcholine-co-n-stearyl methacrylate), Stimulates Insulin Release from RINm5F Insulinoma Cells

合成高分子,2-メタクリロイルヒドロキシエチルホスホリルコリン・n-ステアリルメタクリラート共重合体はRINm5Fインシュリノーマ細胞からのインシュリン放出を刺激する

Author (4)： MARUYAMA S (National Inst. of Advanced Industrial Sci. and Technol., Ibaraki, JPN) ,  HU J (National Inst. of Advanced Industrial Sci. and Technol., Ibaraki, JPN) ,  YAMANAKA A (National Inst. of Advanced Industrial Sci. and Technol., Ibaraki, JPN) ,  ICHIMURA T (National Inst. of Advanced Industrial Sci. and Technol., Ibaraki, JPN)
Material： Bioscience, Biotechnology, and Biochemistry  (Bioscience Biotechnology & Biochemistry)
Volume： 68  Issue： 10  Page： 2197-2200  Publication year： Oct. 23, 2004 
JST Material Number： G0021A  ISSN： 0916-8451  CODEN： BBBIEJ  Document type： Article
Article type： 短報  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： copolymer ,...
Semi thesaurus term： insulinoma ,...

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JST classification (2)： Pancreas  (EJ06050Y) ,  Cell physiology in general  (EF02010S)

Reference (6)：

• 1) Ishihara, K., Tsujino, R., Hamada, M., Toyoda, N., and Iwasaki, Y., Stabilized liposomes with phospholipid polymers and their interactions with blood cells. Colloids Surf. B Biointerfaces, 25, 325–333 (2002).
• 2) Iwasaki, Y., Ijuin, M., Mikami, A., Nakabayashi, N., and Ishihara, K., Behavior of blood cells in contact with water-soluble phospholipid polymer. J. Biomed. Mater. Res., 46, 360–367 (1999).
• 3) Gazdar, A. F., Chick, W. L., Oie, H. K., Sims, H. L., King, D. L., Weir, G. C., and Lauris, V., Continuous, clonal, insulin- and somatostatin-secreting cell lines established from a transplantable rat islet cell tumor. Proc. Natl. Acad. Sci. U.S.A., 77, 3519–3523 (1980).
• 4) Lambert, D. G., and Atkins, T. W., Nutrient induced insulin release from an insulinoma derived B-cell line. Acta Diabetol. Lat., 24, 299–304 (1987).
• 5) Komatsu, M., McDermott, A. M., Gillison, S. L., and Sharp, G. W. G., Mastoparan stimulates exocytosis at a Ca²⁺-independent late site in stimulus-secretion coupling. J. Biol. Chem., 268, 23297–23306 (1993).

Terms in the title (6)： 合成高分子 ,  共重合体 ,  インシュリノーマ ,  細胞 ,  インシュリン放出 ,  刺激