Art

J-GLOBAL ID：200902201556870290   Reference number：08A0126299

4-Hydroxydocosahexaenoic acid, a potent peroxisome proliferator-activated receptor γ agonist alleviates the symptoms of DSS-induced colitis

強いペルオキシゾーム増殖剤活性化受容体γアゴニスト,4-ヒドロキシドコサヘキサエン酸はDSS誘導結腸炎の症状を緩和する

Author (11)： YAMAMOTO Keiko (Lab. of Drug Design and Medicinal Chemistry, Showa Pharmaceutical Univ., 3-3165 Higashi-Tamagawagakuen, Machida ...) ,  NINOMIYA Yuichi (Div. of Translational Res., Saitama Medical Univ., 1397-1 Yamane, Hidaka, Saitama 350-1241, JPN) ,  ISEKI Mioko (Div. of Translational Res., Saitama Medical Univ., 1397-1 Yamane, Hidaka, Saitama 350-1241, JPN) ,  NAKACHI Yutaka (Div. of Functional Genomics & Systems Medicine, Res. Center for Genomic Medicine, Saitama Medical Univ., 1397-1 ...) ,  KANESAKI-YATSUKA Yukiko (Div. of Functional Genomics & Systems Medicine, Res. Center for Genomic Medicine, Saitama Medical Univ., 1397-1 ...) ,  YAMANOUE Yu (Inst. of Biomaterials and Bioengineering, Tokyo Medical and Dental Univ., 2-3-10 Kanda-Surugadai, Chiyoda-ku, Tokyo ...) ,  ITOH Toshimasa (Inst. of Biomaterials and Bioengineering, Tokyo Medical and Dental Univ., 2-3-10 Kanda-Surugadai, Chiyoda-ku, Tokyo ...) ,  NISHII Yasuho (Div. of Functional Genomics & Systems Medicine, Res. Center for Genomic Medicine, Saitama Medical Univ., 1397-1 ...) ,  PETROVSKY Nikolai (Diabetes and Endocrinology, Flinders Medical Centre, Bedford Park, SA 5042, AUS) ,  OKAZAKI Yasushi (Div. of Translational Res., Saitama Medical Univ., 1397-1 Yamane, Hidaka, Saitama 350-1241, JPN) ,  OKAZAKI Yasushi (Div. of Functional Genomics & Systems Medicine, Res. Center for Genomic Medicine, Saitama Medical Univ., 1397-1 ...)
Material： Biochemical and Biophysical Research Communications  (BBRC)
Volume： 367  Issue： 3  Page： 566-572  Publication year： Mar. 14, 2008 
JST Material Number： B0118A  ISSN： 0006-291X  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Thesaurus term： *cytosol receptor ,  hypoglycemic drug ,  dextran sulfate ,  *colitis(colon) ,  lipopolysaccharide ,  macrophage ,  nitrogen monoxide ,  nitric oxide synthase ,  interleukin 6 ,  *anti-inflammatory action ,  body weight ,  mouse(animal) ,  unsaturated fatty acid ,  polyene ,  *PPAR gamma ,  omega-3 fatty acid
Semi thesaurus term： antidiabetic ,  *anti-inflammatory action ,  プロモーター流域

JST classification (2)： Biological function  (EB05020M) ,  Digestive system diseases  (GH03000W)

Substance index (1)： Docosahexaenoic acid

Terms in the title (11)： ペルオキシゾーム ,  増殖剤 ,  活性化 ,  受容体 ,  アゴニスト ,  酸 ,  DSS ,  誘導 ,  結腸炎 ,  症状 ,  緩和