Art

J-GLOBAL ID：200902201919609866   Reference number：08A0188638

Rat GnRH Neurons Exhibit Large Conductance Voltage- and Ca²⁺-Activated K⁺ (BK) Currents and Express BK Channel mRNAs

ラットGnRHニューロンは大コンダクタンスの電位依存性およびCa²⁺活性型K⁺(BK)電流を示しBKチャネルmRNAを発現する

Author (8)： HIRAIZUMI Yoshie (Dep. of Physiology and ²Department of Obstetrics and Gynecology, Nippon Medical School) ,  HIRAIZUMI Yoshie (Dep. of Obstetrics and Gynecology, Nippon Medical School) ,  NISHIMURA Ichiro (Dep. of Physiology and ²Department of Obstetrics and Gynecology, Nippon Medical School) ,  ISHII Hirotaka (Dep. of Physiology and ²Department of Obstetrics and Gynecology, Nippon Medical School) ,  TANAKA Nobuyuki (Dep. of Physiology and ²Department of Obstetrics and Gynecology, Nippon Medical School) ,  TAKESHITA Toshiyuki (Dep. of Obstetrics and Gynecology, Nippon Medical School) ,  SAKUMA Yasuo (Dep. of Physiology and ²Department of Obstetrics and Gynecology, Nippon Medical School) ,  KATO Masakatsu (Dep. of Physiology and ²Department of Obstetrics and Gynecology, Nippon Medical School)
Material： Journal of Physiological Sciences  (JPS)
Volume： 58  Issue： 1  Page： 21-29 (J-STAGE)  Publication year： 2008 
JST Material Number： Z0753A  ISSN： 1880-6546  CODEN： JPSOE2  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *Potassium Channels ,...
Semi thesaurus term： *BK channel

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JST classification (2)： Cell physiology in general  (EF02010S) ,  Reproductive physiology in general  (EJ15010E)

Substance index (1)： Charybdotoxin

Reference (36)：

• HILLE, B. Ion channels of excitable membranes. 2001
• SIM, JA. Heterogeneity in the basic membrane properties of post natal gonadotropin-releasing hormone neurons in the mouse. J Neurosci. 2001, 21, 1067-1075
• KATO, M. Characterization of voltage-gated calcium currents in gonadotropin-releasing hormone neurons tagged with green fluorescent protein in rats. Endocrinology. 2003, 144, 5118-5125
• NUNEMAKER, CS. Calcium current subtypes in GnRH neurons. Biol. Reprod. 2003, 69, 1914-1922
• KATO, M. The SK channel blocker apamin inhibits slow afterhyperpolarization currents in rat gonadotropin-releasing hormone neurones. J Physiol (London). 2006, 574, 431-442

Terms in the title (9)： ラット ,  GnRHニューロン ,  コンダクタンス ,  電位依存性 ,  活性 ,  Bk ,  BKチャネル ,  mRNA ,  発現