Art

J-GLOBAL ID：200902202065230538   Reference number：08A1164316

Synthesis of 6-methyl-6H-indolo[3,2-c]isoquinoline and 6-methyl-6H-indolo[2,3-c]isoquinoline: two new unnatural isoquinoline isomers of the cryptolepine series

6-メチル-6H-インドロ[3,2-c]イソキノリン及び6-メチル-6H-インドロ[2,3-c]イソキノリンの合成 2種類の新しいクリプトレピン系非天然イソキノリン異性体

Author (10)： VAN BAELEN Gitte (Dep. of Chemistry, Univ. of Antwerp, Groenenborgerlaan 171, B-2020 Antwerp, BEL) ,  MEYERS Caroline (Dep. of Chemistry, Univ. of Antwerp, Groenenborgerlaan 171, B-2020 Antwerp, BEL) ,  LEMIERE Guy L.F. (Dep. of Chemistry, Univ. of Antwerp, Groenenborgerlaan 171, B-2020 Antwerp, BEL) ,  HOSTYN Steven (Dep. of Chemistry, Univ. of Antwerp, Groenenborgerlaan 171, B-2020 Antwerp, BEL) ,  DOMMISSE Roger (Dep. of Chemistry, Univ. of Antwerp, Groenenborgerlaan 171, B-2020 Antwerp, BEL) ,  MAES Louis (Dep. of Biomedical Sciences, Univ. of Antwerp, Groenenborgerlaan 171, B-2020 Antwerp, BEL) ,  AUGUSTYNS Koen (Dep. of Pharmaceutical Sciences, Universiteitsplein 1, B-2610 Wilrijk, BEL) ,  HAEMERS Achiel (Dep. of Pharmaceutical Sciences, Universiteitsplein 1, B-2610 Wilrijk, BEL) ,  PIETERS Luc (Dep. of Pharmaceutical Sciences, Universiteitsplein 1, B-2610 Wilrijk, BEL) ,  MAES Bert U.W. (Dep. of Chemistry, Univ. of Antwerp, Groenenborgerlaan 171, B-2020 Antwerp, BEL)
Material： Tetrahedron  (Tetrahedron Symposia-in-Print)
Volume： 64  Issue： 51  Page： 11802-11809  Publication year： Dec. 15, 2008 
JST Material Number： E0234A  ISSN： 0040-4020  Document type： Article
Article type： 原著論文  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Thesaurus term： *nitrogen heterocyclic compound ,  *polynuclear aromatic compound ,  chemical synthesis ,  Amination ,  condensation reaction ,  arylation ,  annulation ,  catalytic reaction ,  palladium catalyst ,  palladium complex ,  Suzuki reaction ,  cross coupling reaction ,  nitrene ,  insertion reaction ,  Methylation ,  regiospecific reaction ,  antiprotozoal action ,  cytotoxicity ,  myoblast ,  activation ,  Buchwald-Hartwig amination
Semi thesaurus term： Buchwald-Hartwig反応

JST classification (3)： Other condensed derivatives of pyridine  (CF07097Y) ,  Platinum family element complexes  (CE01100E) ,  Synthesis of drugs  (GV01030F)

Substance index (11)： 2-Bromoaniline ,  4-Bromoisoquinoline ,  N-(2-Bromophenyl)isoquinoline-4-amine ,  11H-Indolo[3,2-c]isoquinoline ,  2-(Pivaloylamino)phenylboronic acid ,  N-[2-(Isoquinoline-4-yl)phenyl]pivalamide ,  2-(Isoquinoline-4-yl)aniline ,  4-(2-Azidophenyl)isoquinoline ,  7H-Indolo[2,3-c]isoquinoline ,  6-Methyl-6H-indolo[3,2-c]isoquinoline ,  6-Methyl-6H-indolo[2,3-c]isoquinoline

Terms in the title (4)： インド ,  イソキノリン ,  クリプトレピン ,  異性体