Art

J-GLOBAL ID：200902203845986770   Reference number：08A0913575

The actin cytoskeleton of kidney podocytes is a direct target of the antiproteinuric effect of cyclosporine A

腎臓足細胞のアクチン細胞骨格は,サイクロスポリンAの抗タンパク尿作用の直接標的である

Author (18)： FAUL Christian (Univ. Miami Miller School of Medicine, Florida, USA) ,  FAUL Christian (Mount Sinai School of Medicine, New York, USA) ,  DONNELLY Mary (Univ. Miami Miller School of Medicine, Florida, USA) ,  DONNELLY Mary (Mount Sinai School of Medicine, New York, USA) ,  MERSCHER-GOMEZ Sandra (Univ. Miami Miller School of Medicine, Florida, USA) ,  MERSCHER-GOMEZ Sandra (Mount Sinai School of Medicine, New York, USA) ,  CHANG Yoon Hee (Mount Sinai School of Medicine, New York, USA) ,  FRANZ Stefan (Mount Sinai School of Medicine, New York, USA) ,  DELFGAAUW Jacqueline (Mount Sinai School of Medicine, New York, USA) ,  CHANG Jer-Ming (Medical Univ., Kaohsiung, TWN) ,  CHOI Hoon Young (Mount Sinai School of Medicine, New York, USA) ,  CAMPBELL Kirk N (Univ. Miami Miller School of Medicine, Florida, USA) ,  CAMPBELL Kirk N (Mount Sinai School of Medicine, New York, USA) ,  KIM Kwanghee (Mount Sinai School of Medicine, New York, USA) ,  REISER Jochen (Univ. Miami Miller School of Medicine, Florida, USA) ,  REISER Jochen (Harvard Medical School, Massachusetts, USA) ,  MUNDEL Peter (Univ. Miami Miller School of Medicine, Florida, USA) ,  MUNDEL Peter (Mount Sinai School of Medicine, New York, USA)
Material： Nature Medicine  (Nat Med)
Volume： 14  Issue： 9  Page： 931-938  Publication year： Sep. 01, 2008 
JST Material Number： W0636A  ISSN： 1078-8956  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Thesaurus term： *epithelial cell ,  kidney ,  cytoskeleton ,  *immunosuppressant ,  proteinuria ,  target ,  *enzyme inhibitor ,  protein ,  transcription factor ,  *immunosuppressive action ,  Rho protein ,  dephosphorylation ,  cathepsin ,  cellular signal transduction ,  *side effect ,  *long term administration ,  *calcineurin ,  polypeptide ,  cyclopeptide
Semi thesaurus term： NFAT ,  Rho GTPase ,  cathepsin L ,  *calcineurin inhibitor ,  *podocyte

JST classification (2)： Basic medicine on urogenital system  (GM01020T) ,  Biological function  (EB03040U)

Substance index (1)： Ciclosporin

Terms in the title (6)： 腎臓 ,  足細胞 ,  アクチン細胞骨格 ,  サイクロスポリンA ,  タンパク尿 ,  標的