Art

J-GLOBAL ID：200902204772537669   Reference number：08A0188284

Isolation of 8′-Phosphate Ester Derivatives of Amicoumacins: Structure-activity Relationship of Hydroxy Amino Acid Moiety

Amicoumacinsの8′-りん酸エステル誘導体の分離:ヒドロキシアミノ酸の一小部分の構造-活性相関

Author (7)： HASHIMOTO Makoto (Reseach Inst. of Pharmaceutical Sciences, Musashino Univ.) ,  TAGUCHI Takaaki (Reseach Inst. of Pharmaceutical Sciences, Musashino Univ.) ,  NISHIDA Satoshi (Reseach Inst. of Pharmaceutical Sciences, Musashino Univ.) ,  UENO Kouji (Reseach Inst. of Pharmaceutical Sciences, Musashino Univ.) ,  KOIZUMI Kaio (Reseach Inst. of Pharmaceutical Sciences, Musashino Univ.) ,  ABURADA Masaki (Reseach Inst. of Pharmaceutical Sciences, Musashino Univ.) ,  ICHINOSE Koji (Reseach Inst. of Pharmaceutical Sciences, Musashino Univ.)
Material： Journal of Antibiotics  (J Antibiot)
Volume： 60  Issue： 12  Page： 752-756 (J-STAGE)  Publication year： 2007 
JST Material Number： G0489A  ISSN： 0021-8820  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *amino acid ,...
Semi thesaurus term： *hydroxylation ,...

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JST classification (1)： Basic research of antibacterial drugs  (GW17020S)

Reference (23)：

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• OKUNO, T. Structures and phytotoxicity of metabolites from Valsa ceratosperma. Agric Biol Chem. 1986, 50, 997-1001
• KROHN, K. Dihydroisocoumarins from fungi : isolation, structure elucidation, circular dichroism and biological activity. Phytochemistry. 1997, 45, 313-320
• ITOH, J. Amicoumacin-A, a new antibiotic with strong antiinflammatory and antiulcer activity. J Antibiot. 1981, 34, 611-613
• ITOH, J. Isolation, Physicochemical properties and biological activities of amicoumacins produced by Bacillus pumilus. Agric Biol Chem. 1982, 46, 1255-1259

Terms in the title (5)： りん酸 ,  エステル誘導体 ,  酸 ,  活性 ,  相関