Art
J-GLOBAL ID：200902205876852996   Reference number：09A1117725

Impact of trough serum level on radiographic and clinical response to infliximab plus methotrexate in patients with rheumatoid arthritis: results from the RISING study

関節リウマチ患者におけるメトトレキセート併用インフリキシマブに対する放射線反応および臨床反応に及ぼすトラフ血清中濃度の影響 RISING試験結果
Author (5)：
TAKEUCHI Tsutomu

About TAKEUCHI Tsutomu

(Saitama Medical Univ., Saitama, JPN)

About Saitama Medical Univ., Saitama, JPN

, 
MIYASAKA Nobuyuki

About MIYASAKA Nobuyuki

(Tokyo Medical and Dental Univ., Tokyo, JPN)

About Tokyo Medical and Dental Univ., Tokyo, JPN

, 
INOUE Kazuhiko

About INOUE Kazuhiko

(Tokyo Women’s Medical Univ., Tokyo, JPN)

About Tokyo Women’s Medical Univ., Tokyo, JPN

, 
ABE Tohru

About ABE Tohru

(Saitama Medical Univ., Saitama, JPN)

About Saitama Medical Univ., Saitama, JPN

, 
KOIKE Takao

About KOIKE Takao

(Hokkaido Univ., Sapporo, JPN)

About Hokkaido Univ., Sapporo, JPN


Material：
Modern Rheumatology  (Mod Rheumatol)

About Modern Rheumatology


Volume： 19  Issue： 5  Page： 478-487  Publication year： 2009 
JST Material Number： L5142A  ISSN： 1439-7595  Document type： Article
Article type： 原著論文  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)
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human

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,...
Semi thesaurus term：
Thesaurus term/Semi thesaurus term
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*rheumatoid arthritis

About rheumatoid arthritis

,...
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JST classification (2)：
JST classification
Category name(code) classified by JST.
Clinical application of anti-inflammatory drugs 
(GW15020E)

About Clinical application of anti-inflammatory drugs

,  Drug therapy(=pharmacotherapy)for musculoskeletal diseases 
(GG05020D)

About Drug therapy(=pharmacotherapy)for musculoskeletal diseases

Substance index (1)：
Substance index
Chemical Substance indexed to the Article.
Methotrexate

About Methotrexate

Reference (27)：
  • WOLFE, F. The longterm outcomes of rheumatoid arthritis : work disability : a prospective 18 year study of 823 patients. J Rheumatol. 1998, 25, 2108-2117
  • MAINI, RN. Therapeutic efficacy of multiple intravenous infusions of anti-tumor necrosis factor monoclonal antibody combined with low-dose weekly methotrexate in rheumatoid arthritis. Arthritis Rheum. 1998, 41, 1552-1563
  • LIPSKY, PE. Infliximab and methotrexate in the treatment of rheumatoid arthritis. N Engl J Med. 2000, 343, 1594-1602
  • ST CLAIR, EW. Combination of infliximab and methotrexate therapy for early rheumatoid arthritis : a randomized, controlled trial. Arthritis Rheum. 2004, 50, 3432-3443
  • WESTHOVENS, R. The safety of infliximab, combined with background treatments, among patients with rheumatoid arthritis and various comorbidities : a large, randomized, placebo-controlled trial. Arthritis Rheum. 2006, 54, 1075-1086
ｍore...
Terms in the title (10)：
Terms in the title
Keywords automatically extracted from the title.
関節リウマチ

About 関節リウマチ

, 
患者

About 患者

, 
メトトレキセート

About メトトレキセート

, 
併用

About 併用

, 
インフリキシマブ

About インフリキシマブ

, 
放射線

About 放射線

, 
臨床

About 臨床

, 
トラフ

About トラフ

, 
血清中濃度

About 血清中濃度

, 
試験

About 試験


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