Art

J-GLOBAL ID：200902206378976021   Reference number：09A0191719

Stereoselective Synthesis of Nipecotic Acid Derivatives via Palladium-Catalyzed Decarboxylative Cyclization of γ-Methylidene-δ-valerolactones with Imines

γ-メチリデン-δ-バレロラクトン類とイミン類とのパラジウム触媒による脱炭酸環化を経由してのニペコチン酸誘導体の立体選択的合成

Author (3)： SHINTANI Ryo (Kyoto Univ., Kyoto, JPN) ,  MURAKAMI Masataka (Kyoto Univ., Kyoto, JPN) ,  HAYASHI Tamio (Kyoto Univ., Kyoto, JPN)
Material： Organic Letters  (Org Lett)
Volume： 11  Issue： 2  Page： 457-459  Publication year： Jan. 15, 2009 
JST Material Number： W1171A  ISSN： 1523-7060  CODEN： ORLEF7  Document type： Article
Article type： 短報  Country of issue： United States (USA)  Language： ENGLISH (EN)

Thesaurus term： asymmetric synthesis ,  carboxylic acid ,  *nitrogen heterocyclic compound ,  *palladium catalyst ,  decarboxylation reaction ,  cyclization reaction ,  imine ,  lactone ,  functional group protection
Semi thesaurus term： Nipecotic Acids

JST classification (2)： Pyridines  (CF07095Q) ,  Nobel metal catalysts  (CB06122I)

Substance index (15)： 1-(Diethoxyphosphinyl)-2β,3-diphenyl-5-methylenepiperidine-3β-carboxylic acid methyl ester ,  1-(Diethoxyphosphinyl)-2β-(2-methylphenyl)-3-phenyl-5-methylenepiperidine-3β-carboxylic acid methyl ester ,  1-(Diethoxyphosphinyl)-2β-phenyl-3-(2-naphthyl)-5-methylenepiperidine-3β-carboxylic acid methyl ester ,  1-(Diethoxyphosphinyl)-2β-phenyl-3-(3-thienyl)-5-methylenepiperidine-3β-carboxylic acid methyl ester ,  1-(Diethoxyphosphinyl)-2β-phenyl-3-(3-methylphenyl)-5-methylenepiperidine-3β-carboxylic acid methyl ester ,  1-(Diethoxyphosphinyl)-2β-phenyl-3-(4-methoxyphenyl)-5-methylenepiperidine-3β-carboxylic acid methyl ester ,  1-(Diethoxyphosphinyl)-2β-phenyl-3-benzyl-5-methylenepiperidine-3β-carboxylic acid methyl ester ,  2-Oxo-3-(2-naphthyl)-5-methylenetetrahydro-2H-pyran-3-carboxylic acid methyl ester ,  2-Oxo-3-(3-thienyl)-5-methylenetetrahydro-2H-pyran-3-carboxylic acid methyl ester ,  2-Oxo-3-(3-methylphenyl)-5-methylenetetrahydro-2H-pyran-3-carboxylic acid methyl ester ,  2-Oxo-3-(4-methoxyphenyl)-5-methylenetetrahydro-2H-pyran-3-carboxylic acid methyl ester ,  2-Oxo-3-phenyl-5-methylenetetrahydro-2H-pyran-3-carboxylic acid methyl ester ,  2-Oxo-3-benzyl-5-methylenetetrahydro-2H-pyran-3-carboxylic acid methyl ester ,  N-(2-Methylbenzylidene)amidophosphoric acid diethyl ester ,  N-Benzylideneamidophosphoric acid diethyl ester

Terms in the title (8)： δ-バレロラクトン ,  イミン類 ,  パラジウム触媒 ,  脱炭酸 ,  環化 ,  ニペコチン酸 ,  誘導体 ,  立体選択的合成