Association of CYP2A6 Gene Deletion with Cigarette Smoking Status in Japanese Adults.

ANDO M; HAMAJIMA N; ARIYOSHI N; KAMATAKI T; MATSUO K; OHNO Y

Art

J-GLOBAL ID：200902206681027865 Reference number：03A0328199

Association of CYP2A6 Gene Deletion with Cigarette Smoking Status in Japanese Adults.

日本の成人におけるCYP2A6遺伝子欠失の喫煙状態との関係

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Material：
Volume： 13 Issue： 3 Page： 176-181 Publication year： May. 2003
JST Material Number： L3909A ISSN： 0917-5040 Document type： Article
Article type：原著論文 Country of issue： Japan (JPN) Language： ENGLISH (EN)

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Population genetics , Tobacco(=cigarette) , Public health , Enzyme physiology

Reference (35)：

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NAKAJIMA, M. Role of human cytochrome P4502A6 in C-oxidation of nicotine. Drug Metab Dispos. 1996, 24, 1212-1217
MESSINA, ES. A major role for CYP2A6 in nicotine C-oxidation by human liver microsomes. J Pharmacol Exp Ther. 1997, 282, 1608-1614
YAMANO, S. The CYP2A3 gene product catalyzes coumarin 7-hydroxylation in human liver microsomes. Biochemistry. 1990, 29, 1322-1329
FERNANDEZ-SALGUERO, P. A genetic poly-morphism in coumarin 7-hydroxylation : sequence of the human CYP2A genes and identification of variant CYP2A6 alleles. Am J Hum Genet. 1995, 57, 651-660

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