Art

J-GLOBAL ID：200902206787817784   Reference number：08A1000191

Mre11 Dimers Coordinate DNA End Bridging and Nuclease Processing in Double-Strand-Break Repair

Mre11二量体は二本鎖切断修復においてDNA末端架橋およびヌクレアーゼ処理を協調させる

Author (22)： WILLIAMS R. Scott (Dep. of Molecular Biology, The Scripps Res. Inst., 10550 North Torrey Pines Road, MB4, La Jolla, CA 92037, USA) ,  WILLIAMS R. Scott (Skaggs Inst. for Chemical Biology, The Scripps Res. Inst., 10550 North Torrey Pines Road, MB4, La Jolla, CA 92037, USA) ,  MONCALIAN Gabriel (Dep. of Molecular Biology, The Scripps Res. Inst., 10550 North Torrey Pines Road, MB4, La Jolla, CA 92037, USA) ,  MONCALIAN Gabriel (Skaggs Inst. for Chemical Biology, The Scripps Res. Inst., 10550 North Torrey Pines Road, MB4, La Jolla, CA 92037, USA) ,  WILLIAMS Jessica S. (Dep. of Molecular Biology, The Scripps Res. Inst., 10550 North Torrey Pines Road, MB4, La Jolla, CA 92037, USA) ,  YAMADA Yoshiki (Dep. of Molecular Biology, The Scripps Res. Inst., 10550 North Torrey Pines Road, MB4, La Jolla, CA 92037, USA) ,  LIMBO Oliver (Dep. of Molecular Biology, The Scripps Res. Inst., 10550 North Torrey Pines Road, MB4, La Jolla, CA 92037, USA) ,  SHIN David S. (Dep. of Molecular Biology, The Scripps Res. Inst., 10550 North Torrey Pines Road, MB4, La Jolla, CA 92037, USA) ,  SHIN David S. (Skaggs Inst. for Chemical Biology, The Scripps Res. Inst., 10550 North Torrey Pines Road, MB4, La Jolla, CA 92037, USA) ,  GROOCOCK Lynda M. (Dep. of Molecular Biology, The Scripps Res. Inst., 10550 North Torrey Pines Road, MB4, La Jolla, CA 92037, USA) ,  CAHILL Dana (The Radiation Oncology Res. Lab., Dep. of Radiation Oncology, Univ. of Maryland School of Medicine, Baltimore, MD ...) ,  HITOMI Chiharu (Dep. of Molecular Biology, The Scripps Res. Inst., 10550 North Torrey Pines Road, MB4, La Jolla, CA 92037, USA) ,  HITOMI Chiharu (Skaggs Inst. for Chemical Biology, The Scripps Res. Inst., 10550 North Torrey Pines Road, MB4, La Jolla, CA 92037, USA) ,  GUENTHER Grant (Dep. of Molecular Biology, The Scripps Res. Inst., 10550 North Torrey Pines Road, MB4, La Jolla, CA 92037, USA) ,  MOIANI Davide (Dep. of Molecular Biology, The Scripps Res. Inst., 10550 North Torrey Pines Road, MB4, La Jolla, CA 92037, USA) ,  MOIANI Davide (Skaggs Inst. for Chemical Biology, The Scripps Res. Inst., 10550 North Torrey Pines Road, MB4, La Jolla, CA 92037, USA) ,  CARNEY James P. (The Radiation Oncology Res. Lab., Dep. of Radiation Oncology, Univ. of Maryland School of Medicine, Baltimore, MD ...) ,  RUSSELL Paul (Dep. of Molecular Biology, The Scripps Res. Inst., 10550 North Torrey Pines Road, MB4, La Jolla, CA 92037, USA) ,  RUSSELL Paul (Dep. of Cell Biology, The Scripps Res. Inst., 10550 North Torrey Pines Road, MB4, La Jolla, CA 92037, USA) ,  TAINER John A. (Dep. of Molecular Biology, The Scripps Res. Inst., 10550 North Torrey Pines Road, MB4, La Jolla, CA 92037, USA) ,  TAINER John A. (Skaggs Inst. for Chemical Biology, The Scripps Res. Inst., 10550 North Torrey Pines Road, MB4, La Jolla, CA 92037, USA) ,  TAINER John A. (Life Sciences Div., Dep. of Molecular Biology, Lawrence Berkeley National Lab., Berkeley, CA 94720, USA)
Material： Cell (Cambridge, Mass.)  (Cell (Camb. Mass.))
Volume： 135  Issue： 1  Page： 97-109  Publication year： Oct. 03, 2008 
JST Material Number： A0707B  ISSN： 0092-8674  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Thesaurus term： *DNA binding protein ,  dimer ,  DNA double strand break ,  *DNA Repair ,  serine-threonine kinase ,  ataxia telangiectasia ,  nuclear protein ,  Archaea ,  endonuclease ,  carcinogenicity ,  protein complex ,  DNA Replication ,  dimerization ,  helix structure ,  hydrophobic interaction ,  enzyme activity ,  genetic toxicity ,  Saccharomyces cerevisiae ,  Pyrococcus furiosus ,  replicating fork ,  Schizosaccharomyces pombe ,  *Mre11 ,  RAD50 protein ,  NBS1 ,  microorganism ,  Yeasts ,  Ascomycetous yeast ,  Saccharomycetes ,  Saccharomycetales
Semi thesaurus term： Schizosaccharomyces pombe ,  *Mre11 ,  ATM ,  Rad50 ,  NBS1 ,  MRN

JST classification (2)： Biological function  (EB03040U) ,  Molecular genetics in general  (EC02010J)

Terms in the title (8)： Mre11 ,  二量体 ,  二本鎖切断 ,  修復 ,  DNA ,  架橋 ,  ヌクレアーゼ ,  協調