Drug Development Targeting the Glycogen Synthase Kinase-3β (GSK-3β)-Mediated Signal Transduction Pathway:The Role of GSK-3β in the Maintenance of Steady-State Levels of Insulin Receptor Signaling Molecules and Na<sub>v</sub>1.7 Sodium Channel in Adrenal Chromaffin Cells

NEMOTO Takayuki; YANAGITA Toshihiko; KANAI Tasuku; WADA Akihiko

Art

J-GLOBAL ID：200902206864085740 Reference number：09A0189245

Drug Development Targeting the Glycogen Synthase Kinase-3β (GSK-3β)-Mediated Signal Transduction Pathway:The Role of GSK-3β in the Maintenance of Steady-State Levels of Insulin Receptor Signaling Molecules and Na_v1.7 Sodium Channel in Adrenal Chromaffin Cells

グリコーゲンシンターゼキナーゼ-3β(GSK-3β)介在性のシグナル伝達経路を標的とした創薬:副腎クロム親和性細胞中のインスリン受容体シグナル伝達分子の定常状態レベルの維持とNa_v1.7ナトリウムチャネルにおけるGSK-3βの役割

Publisher site Copy service {{ this.onShowCLink("http://jdream3.com/copy/?sid=JGLOBAL&noSystem=1&documentNoArray=09A0189245&COPY=1") }}
Access JDreamⅢ for advanced search and analysis. {{ this.onShowJLink("http://jdream3.com/lp/jglobal/index.html?docNo=09A0189245&from=J-GLOBAL&jstjournalNo=G0813A") }}

Author (4)： , , ,
Material：
Volume： 109 Issue： 2 Page： 157-161 (J-STAGE) Publication year： 2009
JST Material Number： G0813A ISSN： 1347-8613 Document type： Article
Article type：文献レビュー Country of issue： Japan (JPN) Language： ENGLISH (EN)

,...
,...

To see more with JDream III (charged). {{ this.onShowAbsJLink("http://jdream3.com/lp/jglobal/index.html?docNo=09A0189245&from=J-GLOBAL&jstjournalNo=G0813A") }}

Research and development , Cell physiology in general

Reference (38)：

DOBLE, BW. GSK-3 : tricks of the trade for a multitasking kinase. J Cell Sci. 2003, 116, 1175-1186
JOPE, RS. The glamour and gloom of glycogen synthase kinase-3. Trends Biochem Sci. 2004, 29, 95-102
JOPE, RS. Glycogen synthase kinase-3 (GSK3) : inflammation, diseases, and therapeutics. Neurochem Res. 2007, 32, 577-595
PAP, M. Role of glycogen synthase kinase-3 in the phosphatidylinositol 3-kinase/Akt cell survival pathway. J Biol Chem. 1998, 273, 19929-19932
HOEFLICH, KP. Requirement for glycogen synthase kinase-3β in cell survival and NF-κB activation. Nature. 2000, 406, 86-90

ｍore...

, , , , , , , , , , , ,

Return to Previous Page

Drug Development Targeting the Glycogen Synthase Kinase-3β (GSK-3β)-Mediated Signal Transduction Pathway:The Role of GSK-3β in the Maintenance of Steady-State Levels of Insulin Receptor Signaling Molecules and Nav1.7 Sodium Channel in Adrenal Chromaffin Cells

Drug Development Targeting the Glycogen Synthase Kinase-3β (GSK-3β)-Mediated Signal Transduction Pathway:The Role of GSK-3β in the Maintenance of Steady-State Levels of Insulin Receptor Signaling Molecules and Na_v1.7 Sodium Channel in Adrenal Chromaffin Cells