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J-GLOBAL ID：200902207751409759   Reference number：09A1282564

Triterpene Glycosides from the Whole Plant of Anemone hupehensis var. japonica and Their Cytotoxic Activity

Anemone hupehensis var. japonica(キンポウゲ科)の全植物体からのトリテルペングリコシドおよびその細胞毒性活性

Author (5)： YOKOSUKA Akihito (Lab. of Medicinal Pharmacognosy, School of Pharmacy, Tokyo Univ. of Pharmacy and Life Sciences) ,  SANO Tomoe (Lab. of Medicinal Pharmacognosy, School of Pharmacy, Tokyo Univ. of Pharmacy and Life Sciences) ,  HASHIMOTO Ken (Dep. of Diagnostic and Therapeutic Sciences, School of Dentistry, Meikai Univ.) ,  SAKAGAMI Hiroshi (Dep. of Diagnostic and Therapeutic Sciences, School of Dentistry, Meikai Univ.) ,  MIMAKI Yoshihiro (Lab. of Medicinal Pharmacognosy, School of Pharmacy, Tokyo Univ. of Pharmacy and Life Sciences)
Material： Chemical and Pharmaceutical Bulletin  (Chemical & Pharmaceutical Bulletin)
Volume： 57  Issue： 12  Page： 1425-1430 (J-STAGE)  Publication year： 2009 
JST Material Number： G0504A  ISSN： 0009-2363  CODEN： CPBTAL  Document type： Article
Article type： 短報  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *glycoside ,  *pentacyclic triterpene ,  oligosaccharide ,  *Ranunculaceae ,  medicinal plant ,  secondary metabolite ,  molecular structure ,  cytotoxicity ,  tumor cell ,  Electrospray Ionization Mass Spectrometry ,  proton magnetic resonance ,  13C NMR ,  two-dimensional NMR ,  hydrolysis
Semi thesaurus term： Anemone hupehensis var. japonica

JST classification (2)： Glycosides  (CF10057O) ,  Plant biochemistry  (EH01050J)

Substance index (3)： 3β-[2-O-(3-O-β-D-Ribopyranosyl-α-L-rhamnopyranosyl)-α-L-arabinopyranosyloxy]oleana-12-ene-28-oic acid 6-O-[4-O-(3-O-β-D-glucopyranosyl-α-L-rhamnopyranosyl)-β-D-glucopyranosyl]-β-D-glucopyranosyl ester ,  3β-[2-O-(3-O-β-D-Ribopyranosyl-4-O-β-D-glucopyranosyl-α-L-rhamnopyranosyl)-α-L-arabinopyranosyloxy]-5α-oleana-12-ene-28-oic acid 6-O-[4-O-(3-O-β-D-glucopyranosyl-α-L-rhamnopyranosyl)-β-D-glucopyranosyl]-β-D-glucopyranosyl ester ,  3β-[2-O-(3-O-β-D-Ribopyranosyl-α-L-rhamnopyranosyl)-α-L-arabinopyranosyloxy]-23-hydroxyoleana-12-ene-28-oic acid 6-O-[4-O-(3-O-β-D-glucopyranosyl-α-L-rhamnopyranosyl)-β-D-glucopyranosyl]-β-D-glucopyranosyl ester

Reference (14)：

• 1) “The Grand Dictionary of Horticulture,” Vol. 1, ed. by Tsukamoto Y., Shogakukan, Tokyo, 1989, pp. 109—110.
• 2) Jiangsu New Medical College, “The Dictionary of Chinese Medicinal Materials,” Vol. 1, Shanghai Scientific and Technological Press, Shanghai, 1977, pp. 640—641.
• 3) Wang M. K., Chen Y. Z., Wu F. E., Huaxue Xuebao, 52, 609—612 (1994).
• 4) Mizutani K., Ohtani K., Wei J. X., Kasai R., Tanaka O., Planta Med., 50, 327—331 (1984).
• 5) Dubois M. A., Ilyas M., Wagner H., Planta Med., 52, 80—83 (1986).

Terms in the title (4)： Anemone ,  キンポウゲ科 ,  植物体 ,  細胞毒性活性